ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

CCR4-NOT transcription complex subunit 9

Intramolecular
Cysteine 167 and cysteine 235
A redox-regulated disulphide may form within CCR4-NOT transcription complex subunit 9 between cysteines 167 and 235. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
26
PDB code
5lsw
Structure name
a caf40-binding motif facilitates recruitment of the ccr4-not complex to mrnas targeted by drosophila roquin
Structure deposition date
2016-09-05
Thiol separation (Å)
10
Half-sphere exposure sum ?
80
Minimum pKa ?
12
% buried
100
Peptide accession
Q92600
Residue number A
167
Residue number B
235
Peptide name
CCR4-NOT transcription complex subunit 9

Ligandability

Cysteine 167 of CCR4-NOT transcription complex subunit 9

Cysteine 235 of CCR4-NOT transcription complex subunit 9

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