Serine protease HTRA1
Intramolecular
Cysteine 37 and cysteine 62
Cysteine 41 and cysteine 64
Cysteine 46 and cysteine 65
Cysteine 76 and cysteine 89
Cysteine 112 and cysteine 130
Cysteine 83 and cysteine 110
Cysteine 53 and cysteine 68
Cysteine 46 and cysteine 64
Cysteine 76 and cysteine 110
Cysteine 76 and cysteine 83
More...Cysteine 64 and cysteine 65
Cysteine 41 and cysteine 46
Cysteine 83 and cysteine 89
Cysteine 89 and cysteine 110
Cysteine 41 and cysteine 65
Cysteine 62 and cysteine 64
Cysteine 37 and cysteine 64
Cysteine 41 and cysteine 62
Cysteine 62 and cysteine 65
Cysteine 37 and cysteine 41
Cysteine 46 and cysteine 62
Cysteine 110 and cysteine 130
Cysteine 83 and cysteine 130
3tjq A 37 A 62
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 37 and 62.
Details
Redox score ?
88
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
33
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
37
Residue number B
62
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 37 of Serine protease HTRA1
Cysteine 62 of Serine protease HTRA1
3tjq A 41 A 64
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 41 and 64.
Details
Redox score ?
88
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
38
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
41
Residue number B
64
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 41 of Serine protease HTRA1
Cysteine 64 of Serine protease HTRA1
3tjq A 46 A 65
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 46 and 65.
Details
Redox score ?
88
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
40
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
46
Residue number B
65
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 46 of Serine protease HTRA1
Cysteine 65 of Serine protease HTRA1
3tjq A 76 A 89
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 76 and 89.
Details
Redox score ?
87
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
76
Residue number B
89
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 76 of Serine protease HTRA1
Cysteine 89 of Serine protease HTRA1
3tjq A 112 A 130
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 112 and 130.
Details
Redox score ?
84
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
112
Residue number B
130
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 112 of Serine protease HTRA1
Cysteine 130 of Serine protease HTRA1
3tjq A 83 A 110
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 83 and 110.
Details
Redox score ?
84
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
83
Residue number B
110
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 83 of Serine protease HTRA1
Cysteine 110 of Serine protease HTRA1
3tjq A 53 A 68
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 53 and 68.
Details
Redox score ?
84
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
53
Residue number B
68
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 53 of Serine protease HTRA1
Cysteine 68 of Serine protease HTRA1
3tjq A 46 A 64
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 46 and 64.
Details
Redox score ?
78
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
4
Half-sphere exposure sum ?
36
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
46
Residue number B
64
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 46 of Serine protease HTRA1
Cysteine 64 of Serine protease HTRA1
3tjq A 76 A 110
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 76 and 110.
Details
Redox score ?
78
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
4
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
76
Residue number B
110
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 76 of Serine protease HTRA1
Cysteine 110 of Serine protease HTRA1
3tjq A 76 A 83
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 76 and 83.
Details
Redox score ?
76
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
4
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
76
Residue number B
83
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 76 of Serine protease HTRA1
Cysteine 83 of Serine protease HTRA1
3tjq A 64 A 65
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 64 and 65.
Details
Redox score ?
75
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
4
Half-sphere exposure sum ?
44
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
64
Residue number B
65
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 64 of Serine protease HTRA1
Cysteine 65 of Serine protease HTRA1
3tjq A 41 A 46
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 41 and 46.
Details
Redox score ?
74
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
5
Half-sphere exposure sum ?
34
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
41
Residue number B
46
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 41 of Serine protease HTRA1
Cysteine 46 of Serine protease HTRA1
3tjq A 83 A 89
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 83 and 89.
Details
Redox score ?
69
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
4
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
83
Residue number B
89
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 83 of Serine protease HTRA1
Cysteine 89 of Serine protease HTRA1
3tjq A 89 A 110
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 89 and 110.
Details
Redox score ?
67
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
5
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
89
Residue number B
110
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 89 of Serine protease HTRA1
Cysteine 110 of Serine protease HTRA1
3tjq A 41 A 65
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 41 and 65.
Details
Redox score ?
67
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
5
Half-sphere exposure sum ?
42
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
41
Residue number B
65
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 41 of Serine protease HTRA1
Cysteine 65 of Serine protease HTRA1
3tjq A 62 A 64
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 62 and 64. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
57
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
7
Half-sphere exposure sum ?
41
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
62
Residue number B
64
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 62 of Serine protease HTRA1
Cysteine 64 of Serine protease HTRA1
3tjq A 37 A 64
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 37 and 64. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
51
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
32
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
37
Residue number B
64
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 37 of Serine protease HTRA1
Cysteine 64 of Serine protease HTRA1
3tjq A 41 A 62
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 41 and 62. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
8
Half-sphere exposure sum ?
39
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
41
Residue number B
62
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 41 of Serine protease HTRA1
Cysteine 62 of Serine protease HTRA1
3tjq A 62 A 65
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 62 and 65. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
8
Half-sphere exposure sum ?
45
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
62
Residue number B
65
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 62 of Serine protease HTRA1
Cysteine 65 of Serine protease HTRA1
3tjq A 37 A 41
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 37 and 41. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
10
Half-sphere exposure sum ?
30
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
37
Residue number B
41
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 37 of Serine protease HTRA1
Cysteine 41 of Serine protease HTRA1
3tjq A 46 A 62
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 46 and 62. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
10
Half-sphere exposure sum ?
37
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
46
Residue number B
62
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 46 of Serine protease HTRA1
Cysteine 62 of Serine protease HTRA1
3tjq A 110 A 130
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 110 and 130. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
110
Residue number B
130
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 110 of Serine protease HTRA1
Cysteine 130 of Serine protease HTRA1
3tjq A 83 A 130
A redox-regulated disulphide may form within Serine protease HTRA1 between cysteines 83 and 130. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
3tjq
Structure name
n-domain of htra1
Structure deposition date
2011-08-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q92743
Residue number A
83
Residue number B
130
Peptide name
Serine protease HTRA1
Ligandability
Cysteine 83 of Serine protease HTRA1
Cysteine 130 of Serine protease HTRA1
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