Secreted frizzled-related protein 3
Intermolecular
Cysteine 108 and cysteine 108
Cysteine 108 and cysteine 147
Cysteine 35 and cysteine 35
Cysteine 35 and cysteine 96
Cysteine 147 and cysteine 147
Cysteine 96 and cysteine 96
Intramolecular
Cysteine 80 and cysteine 119
Cysteine 43 and cysteine 89
Cysteine 112 and cysteine 136
1ijx A 76 C 76
A redox-regulated disulphide may form between two units of Secreted frizzled-related protein 3 at cysteines 108 and 108 (76 and 76 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
1ijx
Structure name
crystal structure of the cysteine-rich domain of secreted frizzled- related protein 3 (sfrp-3;fzb)
Structure deposition date
2001-04-30
Thiol separation (Å)
6
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide A name
Secreted frizzled-related protein 3
Peptide B name
Secreted frizzled-related protein 3
Peptide A accession
P97401
Peptide B accession
P97401
Peptide A residue number
108
Peptide B residue number
108
Ligandability
1ijx A 76 C 115
A redox-regulated disulphide may form between two units of Secreted frizzled-related protein 3 at cysteines 108 and 147 (76 and 115 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
1ijx
Structure name
crystal structure of the cysteine-rich domain of secreted frizzled- related protein 3 (sfrp-3;fzb)
Structure deposition date
2001-04-30
Thiol separation (Å)
7
Half-sphere exposure sum ?
81
Minimum pKa ?
nan
% buried
nan
Peptide A name
Secreted frizzled-related protein 3
Peptide B name
Secreted frizzled-related protein 3
Peptide A accession
P97401
Peptide B accession
P97401
Peptide A residue number
108
Peptide B residue number
147
Ligandability
Cysteine 108 of Secreted frizzled-related protein 3
Cysteine 147 of Secreted frizzled-related protein 3
1ijx B 3 E 3
A redox-regulated disulphide may form between two units of Secreted frizzled-related protein 3 at cysteines 35 and 35 (3 and 3 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
1ijx
Structure name
crystal structure of the cysteine-rich domain of secreted frizzled- related protein 3 (sfrp-3;fzb)
Structure deposition date
2001-04-30
Thiol separation (Å)
9
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide A name
Secreted frizzled-related protein 3
Peptide B name
Secreted frizzled-related protein 3
Peptide A accession
P97401
Peptide B accession
P97401
Peptide A residue number
35
Peptide B residue number
35
Ligandability
1ijx A 3 C 64
A redox-regulated disulphide may form between two units of Secreted frizzled-related protein 3 at cysteines 35 and 96 (3 and 64 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
1ijx
Structure name
crystal structure of the cysteine-rich domain of secreted frizzled- related protein 3 (sfrp-3;fzb)
Structure deposition date
2001-04-30
Thiol separation (Å)
10
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide A name
Secreted frizzled-related protein 3
Peptide B name
Secreted frizzled-related protein 3
Peptide A accession
P97401
Peptide B accession
P97401
Peptide A residue number
35
Peptide B residue number
96
Ligandability
Cysteine 35 of Secreted frizzled-related protein 3
Cysteine 96 of Secreted frizzled-related protein 3
1ijx B 115 E 115
A redox-regulated disulphide may form between two units of Secreted frizzled-related protein 3 at cysteines 147 and 147 (115 and 115 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
1ijx
Structure name
crystal structure of the cysteine-rich domain of secreted frizzled- related protein 3 (sfrp-3;fzb)
Structure deposition date
2001-04-30
Thiol separation (Å)
9
Half-sphere exposure sum ?
86
Minimum pKa ?
nan
% buried
nan
Peptide A name
Secreted frizzled-related protein 3
Peptide B name
Secreted frizzled-related protein 3
Peptide A accession
P97401
Peptide B accession
P97401
Peptide A residue number
147
Peptide B residue number
147
Ligandability
1ijx B 64 E 64
A redox-regulated disulphide may form between two units of Secreted frizzled-related protein 3 at cysteines 96 and 96 (64 and 64 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
1ijx
Structure name
crystal structure of the cysteine-rich domain of secreted frizzled- related protein 3 (sfrp-3;fzb)
Structure deposition date
2001-04-30
Thiol separation (Å)
9
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide A name
Secreted frizzled-related protein 3
Peptide B name
Secreted frizzled-related protein 3
Peptide A accession
P97401
Peptide B accession
P97401
Peptide A residue number
96
Peptide B residue number
96
Ligandability
1ijx F 48 F 87
A redox-regulated disulphide may form within Secreted frizzled-related protein 3 between cysteines 80 and 119 (48 and 87 respectively in this structure).
Details
Redox score ?
85
PDB code
1ijx
Structure name
crystal structure of the cysteine-rich domain of secreted frizzled- related protein 3 (sfrp-3;fzb)
Structure deposition date
2001-04-30
Thiol separation (Å)
2
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
P97401
Residue number A
80
Residue number B
119
Peptide name
Secreted frizzled-related protein 3
Ligandability
Cysteine 80 of Secreted frizzled-related protein 3
Cysteine 119 of Secreted frizzled-related protein 3
1ijx F 11 F 57
A redox-regulated disulphide may form within Secreted frizzled-related protein 3 between cysteines 43 and 89 (11 and 57 respectively in this structure).
Details
Redox score ?
83
PDB code
1ijx
Structure name
crystal structure of the cysteine-rich domain of secreted frizzled- related protein 3 (sfrp-3;fzb)
Structure deposition date
2001-04-30
Thiol separation (Å)
2
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
P97401
Residue number A
43
Residue number B
89
Peptide name
Secreted frizzled-related protein 3
Ligandability
Cysteine 43 of Secreted frizzled-related protein 3
Cysteine 89 of Secreted frizzled-related protein 3
1ijx E 80 E 104
A redox-regulated disulphide may form within Secreted frizzled-related protein 3 between cysteines 112 and 136 (80 and 104 respectively in this structure).
Details
Redox score ?
83
PDB code
1ijx
Structure name
crystal structure of the cysteine-rich domain of secreted frizzled- related protein 3 (sfrp-3;fzb)
Structure deposition date
2001-04-30
Thiol separation (Å)
2
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
P97401
Residue number A
112
Residue number B
136
Peptide name
Secreted frizzled-related protein 3
Ligandability
Cysteine 112 of Secreted frizzled-related protein 3
Cysteine 136 of Secreted frizzled-related protein 3
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