X-linked retinitis pigmentosa GTPase regulator
Intramolecular
Cysteine 42 and cysteine 94
Cysteine 42 and cysteine 356
Cysteine 302 and cysteine 356
Cysteine 197 and cysteine 250
Cysteine 250 and cysteine 302
Cysteine 343 and cysteine 356
Cysteine 42 and cysteine 359
4jhp C 42 C 94
A redox-regulated disulphide may form within X-linked retinitis pigmentosa GTPase regulator between cysteines 42 and 94. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
4jhp
Structure name
the crystal structure of the rpgr rcc1-like domain in complex with pde6d
Structure deposition date
2013-03-05
Thiol separation (Å)
7
Half-sphere exposure sum ?
105
Minimum pKa ?
9
% buried
100
Peptide accession
Q92834
Residue number A
42
Residue number B
94
Peptide name
X-linked retinitis pigmentosa GTPase regulator
Ligandability
Cysteine 42 of X-linked retinitis pigmentosa GTPase regulator
Cysteine 94 of X-linked retinitis pigmentosa GTPase regulator
4jhp C 42 C 356
A redox-regulated disulphide may form within X-linked retinitis pigmentosa GTPase regulator between cysteines 42 and 356. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
4jhp
Structure name
the crystal structure of the rpgr rcc1-like domain in complex with pde6d
Structure deposition date
2013-03-05
Thiol separation (Å)
7
Half-sphere exposure sum ?
101
Minimum pKa ?
9
% buried
100
Peptide accession
Q92834
Residue number A
42
Residue number B
356
Peptide name
X-linked retinitis pigmentosa GTPase regulator
Ligandability
Cysteine 42 of X-linked retinitis pigmentosa GTPase regulator
Cysteine 356 of X-linked retinitis pigmentosa GTPase regulator
4jhn C 302 C 356
A redox-regulated disulphide may form within X-linked retinitis pigmentosa GTPase regulator between cysteines 302 and 356. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
4jhn
Structure name
the crystal structure of the rpgr rcc1-like domain
Structure deposition date
2013-03-05
Thiol separation (Å)
7
Half-sphere exposure sum ?
100
Minimum pKa ?
12
% buried
100
Peptide accession
Q92834
Residue number A
302
Residue number B
356
Peptide name
X-linked retinitis pigmentosa GTPase regulator
Ligandability
Cysteine 302 of X-linked retinitis pigmentosa GTPase regulator
Cysteine 356 of X-linked retinitis pigmentosa GTPase regulator
4qam A 197 A 250
A redox-regulated disulphide may form within X-linked retinitis pigmentosa GTPase regulator between cysteines 197 and 250. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
36
PDB code
4qam
Structure name
crystal structure of the rpgr rcc1-like domain in complex with the rpgr-interacting domain of rpgrip1
Structure deposition date
2014-05-05
Thiol separation (Å)
8
Half-sphere exposure sum ?
107
Minimum pKa ?
11
% buried
100
Peptide accession
Q92834
Residue number A
197
Residue number B
250
Peptide name
X-linked retinitis pigmentosa GTPase regulator
Ligandability
Cysteine 197 of X-linked retinitis pigmentosa GTPase regulator
Cysteine 250 of X-linked retinitis pigmentosa GTPase regulator
4jhn B 250 B 302
A redox-regulated disulphide may form within X-linked retinitis pigmentosa GTPase regulator between cysteines 250 and 302. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
36
PDB code
4jhn
Structure name
the crystal structure of the rpgr rcc1-like domain
Structure deposition date
2013-03-05
Thiol separation (Å)
7
Half-sphere exposure sum ?
105
Minimum pKa ?
13
% buried
100
Peptide accession
Q92834
Residue number A
250
Residue number B
302
Peptide name
X-linked retinitis pigmentosa GTPase regulator
Ligandability
Cysteine 250 of X-linked retinitis pigmentosa GTPase regulator
Cysteine 302 of X-linked retinitis pigmentosa GTPase regulator
4qam A 343 A 356
A redox-regulated disulphide may form within X-linked retinitis pigmentosa GTPase regulator between cysteines 343 and 356. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
31
PDB code
4qam
Structure name
crystal structure of the rpgr rcc1-like domain in complex with the rpgr-interacting domain of rpgrip1
Structure deposition date
2014-05-05
Thiol separation (Å)
9
Half-sphere exposure sum ?
79
Minimum pKa ?
12
% buried
100
Peptide accession
Q92834
Residue number A
343
Residue number B
356
Peptide name
X-linked retinitis pigmentosa GTPase regulator
Ligandability
Cysteine 343 of X-linked retinitis pigmentosa GTPase regulator
Cysteine 356 of X-linked retinitis pigmentosa GTPase regulator
4qam A 42 A 359
A redox-regulated disulphide may form within X-linked retinitis pigmentosa GTPase regulator between cysteines 42 and 359. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
30
PDB code
4qam
Structure name
crystal structure of the rpgr rcc1-like domain in complex with the rpgr-interacting domain of rpgrip1
Structure deposition date
2014-05-05
Thiol separation (Å)
9
Half-sphere exposure sum ?
90
Minimum pKa ?
10
% buried
87
Peptide accession
Q92834
Residue number A
42
Residue number B
359
Peptide name
X-linked retinitis pigmentosa GTPase regulator
Ligandability
Cysteine 42 of X-linked retinitis pigmentosa GTPase regulator
Cysteine 359 of X-linked retinitis pigmentosa GTPase regulator
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