ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Mature alpha chain of major histocompatibility complex class I antigen

Intramolecular
Cysteine 101 and cysteine 164
Cysteine 203 and cysteine 259
A redox-regulated disulphide may form within Mature alpha chain of major histocompatibility complex class I antigen between cysteines 101 and 164.

Details

Redox score ?
82
PDB code
1kjv
Structure name
tap-b-associated rat mhc class i molecule
Structure deposition date
2001-12-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
80
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q95565
Residue number A
101
Residue number B
164
Peptide name
Mature alpha chain of major histocompatibility complex class I antigen

Ligandability

Cysteine 101 of Mature alpha chain of major histocompatibility complex class I antigen

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 164 of Mature alpha chain of major histocompatibility complex class I antigen

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Mature alpha chain of major histocompatibility complex class I antigen between cysteines 203 and 259.

Details

Redox score ?
81
PDB code
1kjv
Structure name
tap-b-associated rat mhc class i molecule
Structure deposition date
2001-12-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
83
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q95565
Residue number A
203
Residue number B
259
Peptide name
Mature alpha chain of major histocompatibility complex class I antigen

Ligandability

Cysteine 203 of Mature alpha chain of major histocompatibility complex class I antigen

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 259 of Mature alpha chain of major histocompatibility complex class I antigen

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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