a tool for identifying drug-targetable redox-active disulphides

Vacuolar protein sorting-associated protein 33A

Intramolecular

Cysteine 163 and cysteine 198

A redox-regulated disulphide may form within Vacuolar protein sorting-associated protein 33A between cysteines 163 and 198.

Details

Redox score ?

72

PDB code

Structure name

human vps33a

Structure deposition date

2013-07-09

Thiol separation (Å)

4

Half-sphere exposure sum ?

73

Minimum pK_a ?

8

% buried

76

Peptide accession

Residue number A

163

Residue number B

198

Peptide name

Vacuolar protein sorting-associated protein 33A

Ligandability

Cysteine 163 of Vacuolar protein sorting-associated protein 33A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 198 of Vacuolar protein sorting-associated protein 33A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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