Store-operated calcium entry-associated regulatory factor
Intermolecular
Cysteine 83 and cysteine 320 L
Intramolecular
Cysteine 83 and cysteine 97
Cysteine 66 and cysteine 73
Cysteine 98 and cysteine 320 L
Cysteine 114 and cysteine 130
Cysteine 97 and cysteine 98
Cysteine 83 and cysteine 98
Cysteine 83 and cysteine 130
Cysteine 97 and cysteine 320 L
Cysteine 83 and cysteine 114
More...Cysteine 97 and cysteine 130
Cysteine 97 and cysteine 114
6o2w A 83 B 156
A redox-regulated disulphide may form between two units of Store-operated calcium entry-associated regulatory factor at cysteines 83 and 320 (83 and 156 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
6o2w
Structure name
crystal structure of the saraf luminal domain cys-lock mutant dimer
Structure deposition date
2019-02-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide A name
Store-operated calcium entry-associated regulatory factor
Peptide B name
Store-operated calcium entry-associated regulatory factor
Peptide A accession
Q96BY9
Peptide B accession
Q96BY9
Peptide A residue number
83
Peptide B residue number
320
Ligandability
Cysteine 83 of Store-operated calcium entry-associated regulatory factor
Cysteine 320 of Store-operated calcium entry-associated regulatory factor
6o2u B 83 B 97
A redox-regulated disulphide may form within Store-operated calcium entry-associated regulatory factor between cysteines 83 and 97.
Details
Redox score ?
87
PDB code
6o2u
Structure name
crystal structure of the saraf luminal domain
Structure deposition date
2019-02-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96BY9
Residue number A
83
Residue number B
97
Peptide name
Store-operated calcium entry-associated regulatory factor
Ligandability
Cysteine 83 of Store-operated calcium entry-associated regulatory factor
Cysteine 97 of Store-operated calcium entry-associated regulatory factor
6o2w A 66 A 73
A redox-regulated disulphide may form within Store-operated calcium entry-associated regulatory factor between cysteines 66 and 73.
Details
Redox score ?
86
PDB code
6o2w
Structure name
crystal structure of the saraf luminal domain cys-lock mutant dimer
Structure deposition date
2019-02-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96BY9
Residue number A
66
Residue number B
73
Peptide name
Store-operated calcium entry-associated regulatory factor
Ligandability
Cysteine 66 of Store-operated calcium entry-associated regulatory factor
Cysteine 73 of Store-operated calcium entry-associated regulatory factor
6o2v B 98 B 156
A redox-regulated disulphide may form within Store-operated calcium entry-associated regulatory factor between cysteines 98 and 320 (98 and 156 respectively in this structure).
Details
Redox score ?
79
PDB code
6o2v
Structure name
crystal structure of the saraf luminal domain cys-lock mutant monomer
Structure deposition date
2019-02-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96BY9
Residue number A
98
Residue number B
320
Peptide name
Store-operated calcium entry-associated regulatory factor
Ligandability
Cysteine 98 of Store-operated calcium entry-associated regulatory factor
Cysteine 320 of Store-operated calcium entry-associated regulatory factor
Cysteine 98 in protein A could not be asigned to a Uniprot residue.
6o2v B 114 B 130
A redox-regulated disulphide may form within Store-operated calcium entry-associated regulatory factor between cysteines 114 and 130.
Details
Redox score ?
78
PDB code
6o2v
Structure name
crystal structure of the saraf luminal domain cys-lock mutant monomer
Structure deposition date
2019-02-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
88
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96BY9
Residue number A
114
Residue number B
130
Peptide name
Store-operated calcium entry-associated regulatory factor
Ligandability
Cysteine 114 of Store-operated calcium entry-associated regulatory factor
Cysteine 130 of Store-operated calcium entry-associated regulatory factor
6o2w B 97 B 98
A redox-regulated disulphide may form within Store-operated calcium entry-associated regulatory factor between cysteines 97 and 98. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
6o2w
Structure name
crystal structure of the saraf luminal domain cys-lock mutant dimer
Structure deposition date
2019-02-24
Thiol separation (Å)
7
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96BY9
Residue number A
97
Residue number B
98
Peptide name
Store-operated calcium entry-associated regulatory factor
Ligandability
Cysteine 97 of Store-operated calcium entry-associated regulatory factor
Cysteine 98 of Store-operated calcium entry-associated regulatory factor
Cysteine 98 in protein B could not be asigned to a Uniprot residue.
6o2v B 83 B 98
A redox-regulated disulphide may form within Store-operated calcium entry-associated regulatory factor between cysteines 83 and 98. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
6o2v
Structure name
crystal structure of the saraf luminal domain cys-lock mutant monomer
Structure deposition date
2019-02-24
Thiol separation (Å)
8
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96BY9
Residue number A
83
Residue number B
98
Peptide name
Store-operated calcium entry-associated regulatory factor
Ligandability
Cysteine 83 of Store-operated calcium entry-associated regulatory factor
Cysteine 98 of Store-operated calcium entry-associated regulatory factor
Cysteine 98 in protein B could not be asigned to a Uniprot residue.
6o2u A 83 A 130
A redox-regulated disulphide may form within Store-operated calcium entry-associated regulatory factor between cysteines 83 and 130. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
6o2u
Structure name
crystal structure of the saraf luminal domain
Structure deposition date
2019-02-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96BY9
Residue number A
83
Residue number B
130
Peptide name
Store-operated calcium entry-associated regulatory factor
Ligandability
Cysteine 83 of Store-operated calcium entry-associated regulatory factor
Cysteine 130 of Store-operated calcium entry-associated regulatory factor
6o2v B 97 B 156
A redox-regulated disulphide may form within Store-operated calcium entry-associated regulatory factor between cysteines 97 and 320 (97 and 156 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
6o2v
Structure name
crystal structure of the saraf luminal domain cys-lock mutant monomer
Structure deposition date
2019-02-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96BY9
Residue number A
97
Residue number B
320
Peptide name
Store-operated calcium entry-associated regulatory factor
Ligandability
Cysteine 97 of Store-operated calcium entry-associated regulatory factor
Cysteine 320 of Store-operated calcium entry-associated regulatory factor
6o2v A 83 A 114
A redox-regulated disulphide may form within Store-operated calcium entry-associated regulatory factor between cysteines 83 and 114. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
6o2v
Structure name
crystal structure of the saraf luminal domain cys-lock mutant monomer
Structure deposition date
2019-02-24
Thiol separation (Å)
10
Half-sphere exposure sum ?
81
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96BY9
Residue number A
83
Residue number B
114
Peptide name
Store-operated calcium entry-associated regulatory factor
Ligandability
Cysteine 83 of Store-operated calcium entry-associated regulatory factor
Cysteine 114 of Store-operated calcium entry-associated regulatory factor
6o2v B 97 B 130
A redox-regulated disulphide may form within Store-operated calcium entry-associated regulatory factor between cysteines 97 and 130. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
34
PDB code
6o2v
Structure name
crystal structure of the saraf luminal domain cys-lock mutant monomer
Structure deposition date
2019-02-24
Thiol separation (Å)
10
Half-sphere exposure sum ?
86
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96BY9
Residue number A
97
Residue number B
130
Peptide name
Store-operated calcium entry-associated regulatory factor
Ligandability
Cysteine 97 of Store-operated calcium entry-associated regulatory factor
Cysteine 130 of Store-operated calcium entry-associated regulatory factor
6o2v B 97 B 114
A redox-regulated disulphide may form within Store-operated calcium entry-associated regulatory factor between cysteines 97 and 114. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
33
PDB code
6o2v
Structure name
crystal structure of the saraf luminal domain cys-lock mutant monomer
Structure deposition date
2019-02-24
Thiol separation (Å)
10
Half-sphere exposure sum ?
88
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96BY9
Residue number A
97
Residue number B
114
Peptide name
Store-operated calcium entry-associated regulatory factor
Ligandability
Cysteine 97 of Store-operated calcium entry-associated regulatory factor
Cysteine 114 of Store-operated calcium entry-associated regulatory factor
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