Baculoviral IAP repeat-containing protein 7
Intermolecular
Cysteine 127 and cysteine 127
Intramolecular
Cysteine 252 and cysteine 275
Cysteine 252 and cysteine 272
Cysteine 252 and cysteine 255
Cysteine 255 and cysteine 272
Cysteine 255 and cysteine 275
Cysteine 272 and cysteine 275
Cysteine 124 and cysteine 127
Cysteine 127 and cysteine 151
Cysteine 267 and cysteine 285
More...Cysteine 282 and cysteine 285
Cysteine 124 and cysteine 151
Cysteine 267 and cysteine 282
3f7g A 127 D 127
A redox-regulated disulphide may form between two units of Baculoviral IAP repeat-containing protein 7 at cysteines 127 and 127. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
14
PDB code
3f7g
Structure name
structure of the bir domain from ml-iap bound to a peptidomimetic
Structure deposition date
2008-11-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
92
Minimum pKa ?
19
% buried
100
Peptide A name
Baculoviral IAP repeat-containing protein 7
Peptide B name
Baculoviral IAP repeat-containing protein 7
Peptide A accession
Q96CA5
Peptide B accession
Q96CA5
Peptide A residue number
127
Peptide B residue number
127
Ligandability
4auq B 252 B 275
A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 7 between cysteines 252 and 275.
Details
Redox score ?
88
PDB code
4auq
Structure name
structure of birc7-ubch5b-ub complex
Structure deposition date
2012-05-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
66
Minimum pKa ?
2
% buried
64
Peptide accession
Q96CA5
Residue number A
252
Residue number B
275
Peptide name
Baculoviral IAP repeat-containing protein 7
Ligandability
Cysteine 252 of Baculoviral IAP repeat-containing protein 7
Cysteine 275 of Baculoviral IAP repeat-containing protein 7
4auq B 252 B 272
A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 7 between cysteines 252 and 272.
Details
Redox score ?
87
PDB code
4auq
Structure name
structure of birc7-ubch5b-ub complex
Structure deposition date
2012-05-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
63
Minimum pKa ?
2
% buried
55
Peptide accession
Q96CA5
Residue number A
252
Residue number B
272
Peptide name
Baculoviral IAP repeat-containing protein 7
Ligandability
Cysteine 252 of Baculoviral IAP repeat-containing protein 7
Cysteine 272 of Baculoviral IAP repeat-containing protein 7
4auq E 252 E 255
A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 7 between cysteines 252 and 255.
Details
Redox score ?
84
PDB code
4auq
Structure name
structure of birc7-ubch5b-ub complex
Structure deposition date
2012-05-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
68
Minimum pKa ?
3
% buried
58
Peptide accession
Q96CA5
Residue number A
252
Residue number B
255
Peptide name
Baculoviral IAP repeat-containing protein 7
Ligandability
Cysteine 252 of Baculoviral IAP repeat-containing protein 7
Cysteine 255 of Baculoviral IAP repeat-containing protein 7
4auq B 255 B 272
A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 7 between cysteines 255 and 272.
Details
Redox score ?
77
PDB code
4auq
Structure name
structure of birc7-ubch5b-ub complex
Structure deposition date
2012-05-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
62
Minimum pKa ?
7
% buried
40
Peptide accession
Q96CA5
Residue number A
255
Residue number B
272
Peptide name
Baculoviral IAP repeat-containing protein 7
Ligandability
Cysteine 255 of Baculoviral IAP repeat-containing protein 7
Cysteine 272 of Baculoviral IAP repeat-containing protein 7
4auq E 255 E 275
A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 7 between cysteines 255 and 275.
Details
Redox score ?
76
PDB code
4auq
Structure name
structure of birc7-ubch5b-ub complex
Structure deposition date
2012-05-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
64
Minimum pKa ?
8
% buried
50
Peptide accession
Q96CA5
Residue number A
255
Residue number B
275
Peptide name
Baculoviral IAP repeat-containing protein 7
Ligandability
Cysteine 255 of Baculoviral IAP repeat-containing protein 7
Cysteine 275 of Baculoviral IAP repeat-containing protein 7
4auq E 272 E 275
A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 7 between cysteines 272 and 275.
Details
Redox score ?
72
PDB code
4auq
Structure name
structure of birc7-ubch5b-ub complex
Structure deposition date
2012-05-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
62
Minimum pKa ?
10
% buried
48
Peptide accession
Q96CA5
Residue number A
272
Residue number B
275
Peptide name
Baculoviral IAP repeat-containing protein 7
Ligandability
Cysteine 272 of Baculoviral IAP repeat-containing protein 7
Cysteine 275 of Baculoviral IAP repeat-containing protein 7
3f7g E 124 E 127
A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 7 between cysteines 124 and 127.
Details
Redox score ?
69
PDB code
3f7g
Structure name
structure of the bir domain from ml-iap bound to a peptidomimetic
Structure deposition date
2008-11-09
Thiol separation (Å)
4
Half-sphere exposure sum ?
72
Minimum pKa ?
10
% buried
nan
Peptide accession
Q96CA5
Residue number A
124
Residue number B
127
Peptide name
Baculoviral IAP repeat-containing protein 7
Ligandability
Cysteine 124 of Baculoviral IAP repeat-containing protein 7
Cysteine 127 of Baculoviral IAP repeat-containing protein 7
1oy7 B 127 B 151
A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 7 between cysteines 127 and 151.
Details
Redox score ?
69
PDB code
1oy7
Structure name
structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ml-iap)
Structure deposition date
2003-04-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
88
Minimum pKa ?
10
% buried
100
Peptide accession
Q96CA5
Residue number A
127
Residue number B
151
Peptide name
Baculoviral IAP repeat-containing protein 7
Ligandability
Cysteine 127 of Baculoviral IAP repeat-containing protein 7
Cysteine 151 of Baculoviral IAP repeat-containing protein 7
4auq E 267 E 285
A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 7 between cysteines 267 and 285.
Details
Redox score ?
68
PDB code
4auq
Structure name
structure of birc7-ubch5b-ub complex
Structure deposition date
2012-05-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
76
Minimum pKa ?
10
% buried
nan
Peptide accession
Q96CA5
Residue number A
267
Residue number B
285
Peptide name
Baculoviral IAP repeat-containing protein 7
Ligandability
Cysteine 267 of Baculoviral IAP repeat-containing protein 7
Cysteine 285 of Baculoviral IAP repeat-containing protein 7
4auq B 282 B 285
A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 7 between cysteines 282 and 285.
Details
Redox score ?
68
PDB code
4auq
Structure name
structure of birc7-ubch5b-ub complex
Structure deposition date
2012-05-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
79
Minimum pKa ?
10
% buried
nan
Peptide accession
Q96CA5
Residue number A
282
Residue number B
285
Peptide name
Baculoviral IAP repeat-containing protein 7
Ligandability
Cysteine 282 of Baculoviral IAP repeat-containing protein 7
Cysteine 285 of Baculoviral IAP repeat-containing protein 7
1oy7 E 124 E 151
A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 7 between cysteines 124 and 151. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
1oy7
Structure name
structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ml-iap)
Structure deposition date
2003-04-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
73
Minimum pKa ?
18
% buried
nan
Peptide accession
Q96CA5
Residue number A
124
Residue number B
151
Peptide name
Baculoviral IAP repeat-containing protein 7
Ligandability
Cysteine 124 of Baculoviral IAP repeat-containing protein 7
Cysteine 151 of Baculoviral IAP repeat-containing protein 7
4auq B 267 B 282
A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 7 between cysteines 267 and 282. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
4auq
Structure name
structure of birc7-ubch5b-ub complex
Structure deposition date
2012-05-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
75
Minimum pKa ?
18
% buried
nan
Peptide accession
Q96CA5
Residue number A
267
Residue number B
282
Peptide name
Baculoviral IAP repeat-containing protein 7
Ligandability
Cysteine 267 of Baculoviral IAP repeat-containing protein 7
Cysteine 282 of Baculoviral IAP repeat-containing protein 7
If this tool was useful for finding a disulphide, please cite: