a tool for identifying drug-targetable redox-active disulphides

Phosphopantothenoylcysteine decarboxylase

Intramolecular

Cysteine 116 and cysteine 122

A redox-regulated disulphide may form within Phosphopantothenoylcysteine decarboxylase between cysteines 116 and 122.

Details

Redox score ?

83

PDB code

Structure name

crystal structure of human phosphopantothenoylcysteine decarboxylase

Structure deposition date

2003-09-17

Thiol separation (Å)

2

Half-sphere exposure sum ?

52

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

116

Residue number B

122

Peptide name

Phosphopantothenoylcysteine decarboxylase

Ligandability

Cysteine 116 of Phosphopantothenoylcysteine decarboxylase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 122 of Phosphopantothenoylcysteine decarboxylase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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