ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Netrin-G2

Intramolecular
Cysteine 69 and cysteine 77
Cysteine 171 and cysteine 195
Cysteine 319 and cysteine 344
Cysteine 289 and cysteine 305
Cysteine 287 and cysteine 296
Cysteine 307 and cysteine 316
Cysteine 22 and cysteine 39
Cysteine 61 and cysteine 81
Cysteine 296 and cysteine 305
Cysteine 305 and cysteine 316
More...
Cysteine 289 and cysteine 296
Cysteine 289 and cysteine 316
Cysteine 305 and cysteine 307
Cysteine 287 and cysteine 305
Cysteine 287 and cysteine 289
Cysteine 289 and cysteine 307
Cysteine 296 and cysteine 316
Cysteine 22 and cysteine 316
Cysteine 296 and cysteine 307
Cysteine 22 and cysteine 289
Cysteine 39 and cysteine 316
Cysteine 39 and cysteine 289
Cysteine 22 and cysteine 307
Cysteine 307 and cysteine 344
Cysteine 316 and cysteine 344
Cysteine 22 and cysteine 305
Cysteine 39 and cysteine 307
Cysteine 287 and cysteine 316
Cysteine 39 and cysteine 305
A redox-regulated disulphide may form within Netrin-G2 between cysteines 69 and 77 (52 and 60 respectively in this structure).

Details

Redox score ?
88
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
46
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
69
Residue number B
77
Peptide name
Netrin-G2

Ligandability

Cysteine 69 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 77 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 171 and 195 (154 and 178 respectively in this structure).

Details

Redox score ?
86
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
171
Residue number B
195
Peptide name
Netrin-G2

Ligandability

Cysteine 171 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 195 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 319 and 344 (302 and 327 respectively in this structure).

Details

Redox score ?
86
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
319
Residue number B
344
Peptide name
Netrin-G2

Ligandability

Cysteine 319 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 344 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 289 and 305 (272 and 288 respectively in this structure).

Details

Redox score ?
84
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
289
Residue number B
305
Peptide name
Netrin-G2

Ligandability

Cysteine 289 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 305 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 287 and 296 (270 and 279 respectively in this structure).

Details

Redox score ?
84
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
79
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
287
Residue number B
296
Peptide name
Netrin-G2

Ligandability

Cysteine 287 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 296 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 307 and 316 (290 and 299 respectively in this structure).

Details

Redox score ?
83
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
307
Residue number B
316
Peptide name
Netrin-G2

Ligandability

Cysteine 307 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 316 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 22 and 39 (5 and 22 respectively in this structure).

Details

Redox score ?
82
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
22
Residue number B
39
Peptide name
Netrin-G2

Ligandability

Cysteine 22 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 39 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 61 and 81 (44 and 64 respectively in this structure).

Details

Redox score ?
81
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
61
Residue number B
81
Peptide name
Netrin-G2

Ligandability

Cysteine 61 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 81 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 296 and 305 (279 and 288 respectively in this structure).

Details

Redox score ?
73
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
5
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
296
Residue number B
305
Peptide name
Netrin-G2

Ligandability

Cysteine 296 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 305 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 305 and 316 (288 and 299 respectively in this structure).

Details

Redox score ?
72
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
305
Residue number B
316
Peptide name
Netrin-G2

Ligandability

Cysteine 305 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 316 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 289 and 296 (272 and 279 respectively in this structure).

Details

Redox score ?
71
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
5
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
289
Residue number B
296
Peptide name
Netrin-G2

Ligandability

Cysteine 289 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 296 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 289 and 316 (272 and 299 respectively in this structure).

Details

Redox score ?
67
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
5
Half-sphere exposure sum ?
80
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
289
Residue number B
316
Peptide name
Netrin-G2

Ligandability

Cysteine 289 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 316 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 305 and 307 (288 and 290 respectively in this structure).

Details

Redox score ?
67
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
5
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
305
Residue number B
307
Peptide name
Netrin-G2

Ligandability

Cysteine 305 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 307 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 287 and 305 (270 and 288 respectively in this structure).

Details

Redox score ?
63
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
5
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
287
Residue number B
305
Peptide name
Netrin-G2

Ligandability

Cysteine 287 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 305 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 287 and 289 (270 and 272 respectively in this structure).

Details

Redox score ?
63
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
5
Half-sphere exposure sum ?
86
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
287
Residue number B
289
Peptide name
Netrin-G2

Ligandability

Cysteine 287 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 289 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 289 and 307 (272 and 290 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
59
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
6
Half-sphere exposure sum ?
81
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
289
Residue number B
307
Peptide name
Netrin-G2

Ligandability

Cysteine 289 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 307 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 296 and 316 (279 and 299 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
50
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
8
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
296
Residue number B
316
Peptide name
Netrin-G2

Ligandability

Cysteine 296 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 316 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 22 and 316 (5 and 299 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
48
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
8
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
22
Residue number B
316
Peptide name
Netrin-G2

Ligandability

Cysteine 22 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 316 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 296 and 307 (279 and 290 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
48
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
9
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
296
Residue number B
307
Peptide name
Netrin-G2

Ligandability

Cysteine 296 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 307 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 22 and 289 (5 and 272 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
47
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
9
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
22
Residue number B
289
Peptide name
Netrin-G2

Ligandability

Cysteine 22 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 289 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 39 and 316 (22 and 299 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
46
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
8
Half-sphere exposure sum ?
80
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
39
Residue number B
316
Peptide name
Netrin-G2

Ligandability

Cysteine 39 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 316 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 39 and 289 (22 and 272 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
45
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
8
Half-sphere exposure sum ?
85
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
39
Residue number B
289
Peptide name
Netrin-G2

Ligandability

Cysteine 39 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 289 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 22 and 307 (5 and 290 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
42
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
9
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
22
Residue number B
307
Peptide name
Netrin-G2

Ligandability

Cysteine 22 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 307 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 307 and 344 (290 and 327 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
42
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
10
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
307
Residue number B
344
Peptide name
Netrin-G2

Ligandability

Cysteine 307 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 344 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 316 and 344 (299 and 327 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
42
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
10
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
316
Residue number B
344
Peptide name
Netrin-G2

Ligandability

Cysteine 316 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 344 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 22 and 305 (5 and 288 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
40
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
10
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
22
Residue number B
305
Peptide name
Netrin-G2

Ligandability

Cysteine 22 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 305 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 39 and 307 (22 and 290 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
38
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
9
Half-sphere exposure sum ?
80
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
39
Residue number B
307
Peptide name
Netrin-G2

Ligandability

Cysteine 39 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 307 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 287 and 316 (270 and 299 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
38
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
9
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
287
Residue number B
316
Peptide name
Netrin-G2

Ligandability

Cysteine 287 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 316 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Netrin-G2 between cysteines 39 and 305 (22 and 288 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
38
PDB code
3tbd
Structure name
crystal structure of domain vi and le1 of human netrin-g2
Structure deposition date
2011-08-05
Thiol separation (Å)
10
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96CW9
Residue number A
39
Residue number B
305
Peptide name
Netrin-G2

Ligandability

Cysteine 39 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 305 of Netrin-G2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: