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Hepatitis A virus cellular receptor 1

Intramolecular
Cysteine 46 and cysteine 57
Cysteine 52 and cysteine 104
Cysteine 36 and cysteine 105
Cysteine 57 and cysteine 104
Cysteine 52 and cysteine 57
Cysteine 104 and cysteine 105
Cysteine 57 and cysteine 105
Cysteine 46 and cysteine 104
Cysteine 36 and cysteine 52
Cysteine 36 and cysteine 104
More...
Cysteine 52 and cysteine 105
Cysteine 37 and cysteine 60
Cysteine 46 and cysteine 105
Cysteine 46 and cysteine 52
Cysteine 37 and cysteine 49
A redox-regulated disulphide may form within Hepatitis A virus cellular receptor 1 between cysteines 46 and 57 (29 and 40 respectively in this structure).

Details

Redox score ?
83
PDB code
5dzo
Structure name
crystal structure of human t-cell immunoglobulin and mucin domain protein 1
Structure deposition date
2015-09-25
Thiol separation (Å)
2
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96D42
Residue number A
46
Residue number B
57
Peptide name
Hepatitis A virus cellular receptor 1

Ligandability

Cysteine 46 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 57 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Hepatitis A virus cellular receptor 1 between cysteines 52 and 104 (35 and 87 respectively in this structure).

Details

Redox score ?
82
PDB code
5dzo
Structure name
crystal structure of human t-cell immunoglobulin and mucin domain protein 1
Structure deposition date
2015-09-25
Thiol separation (Å)
2
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96D42
Residue number A
52
Residue number B
104
Peptide name
Hepatitis A virus cellular receptor 1

Ligandability

Cysteine 52 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 104 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Hepatitis A virus cellular receptor 1 between cysteines 36 and 105 (19 and 88 respectively in this structure).

Details

Redox score ?
79
PDB code
5dzo
Structure name
crystal structure of human t-cell immunoglobulin and mucin domain protein 1
Structure deposition date
2015-09-25
Thiol separation (Å)
2
Half-sphere exposure sum ?
79
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96D42
Residue number A
36
Residue number B
105
Peptide name
Hepatitis A virus cellular receptor 1

Ligandability

Cysteine 36 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 105 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Hepatitis A virus cellular receptor 1 between cysteines 57 and 104 (38 and 85 respectively in this structure).

Details

Redox score ?
61
PDB code
5f70
Structure name
crystal structures of human tim members
Structure deposition date
2015-12-07
Thiol separation (Å)
6
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96D42
Residue number A
57
Residue number B
104
Peptide name
Hepatitis A virus cellular receptor 1

Ligandability

Cysteine 57 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 104 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Hepatitis A virus cellular receptor 1 between cysteines 52 and 57 (33 and 38 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
54
PDB code
5f70
Structure name
crystal structures of human tim members
Structure deposition date
2015-12-07
Thiol separation (Å)
8
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96D42
Residue number A
52
Residue number B
57
Peptide name
Hepatitis A virus cellular receptor 1

Ligandability

Cysteine 52 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 57 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Hepatitis A virus cellular receptor 1 between cysteines 104 and 105 (85 and 86 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
48
PDB code
5f70
Structure name
crystal structures of human tim members
Structure deposition date
2015-12-07
Thiol separation (Å)
7
Half-sphere exposure sum ?
83
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96D42
Residue number A
104
Residue number B
105
Peptide name
Hepatitis A virus cellular receptor 1

Ligandability

Cysteine 104 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 105 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Hepatitis A virus cellular receptor 1 between cysteines 57 and 105 (38 and 86 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
47
PDB code
5f70
Structure name
crystal structures of human tim members
Structure deposition date
2015-12-07
Thiol separation (Å)
8
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96D42
Residue number A
57
Residue number B
105
Peptide name
Hepatitis A virus cellular receptor 1

Ligandability

Cysteine 57 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 105 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Hepatitis A virus cellular receptor 1 between cysteines 46 and 104 (27 and 85 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
46
PDB code
5f70
Structure name
crystal structures of human tim members
Structure deposition date
2015-12-07
Thiol separation (Å)
7
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96D42
Residue number A
46
Residue number B
104
Peptide name
Hepatitis A virus cellular receptor 1

Ligandability

Cysteine 46 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 104 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Hepatitis A virus cellular receptor 1 between cysteines 36 and 52 (19 and 35 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
45
PDB code
5dzo
Structure name
crystal structure of human t-cell immunoglobulin and mucin domain protein 1
Structure deposition date
2015-09-25
Thiol separation (Å)
9
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96D42
Residue number A
36
Residue number B
52
Peptide name
Hepatitis A virus cellular receptor 1

Ligandability

Cysteine 36 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 52 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Hepatitis A virus cellular receptor 1 between cysteines 36 and 104 (19 and 87 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
44
PDB code
5dzo
Structure name
crystal structure of human t-cell immunoglobulin and mucin domain protein 1
Structure deposition date
2015-09-25
Thiol separation (Å)
8
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96D42
Residue number A
36
Residue number B
104
Peptide name
Hepatitis A virus cellular receptor 1

Ligandability

Cysteine 36 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 104 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Hepatitis A virus cellular receptor 1 between cysteines 52 and 105 (33 and 86 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
43
PDB code
5f70
Structure name
crystal structures of human tim members
Structure deposition date
2015-12-07
Thiol separation (Å)
9
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96D42
Residue number A
52
Residue number B
105
Peptide name
Hepatitis A virus cellular receptor 1

Ligandability

Cysteine 52 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 105 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Hepatitis A virus cellular receptor 1 homolog between cysteines 37 and 60 (19 and 42 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
43
PDB code
2or8
Structure name
tim-1
Structure deposition date
2007-02-02
Thiol separation (Å)
9
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q5QNS5
Residue number A
37
Residue number B
60
Peptide name
Hepatitis A virus cellular receptor 1 homolog

Ligandability

Cysteine 37 of Hepatitis A virus cellular receptor 1 homolog

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 60 of Hepatitis A virus cellular receptor 1 homolog

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Hepatitis A virus cellular receptor 1 between cysteines 46 and 105 (27 and 86 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
39
PDB code
5f70
Structure name
crystal structures of human tim members
Structure deposition date
2015-12-07
Thiol separation (Å)
8
Half-sphere exposure sum ?
86
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96D42
Residue number A
46
Residue number B
105
Peptide name
Hepatitis A virus cellular receptor 1

Ligandability

Cysteine 46 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 105 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Hepatitis A virus cellular receptor 1 between cysteines 46 and 52 (27 and 33 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
38
PDB code
5f70
Structure name
crystal structures of human tim members
Structure deposition date
2015-12-07
Thiol separation (Å)
9
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96D42
Residue number A
46
Residue number B
52
Peptide name
Hepatitis A virus cellular receptor 1

Ligandability

Cysteine 46 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 52 of Hepatitis A virus cellular receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Hepatitis A virus cellular receptor 1 homolog between cysteines 37 and 49 (19 and 31 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
30
PDB code
2or8
Structure name
tim-1
Structure deposition date
2007-02-02
Thiol separation (Å)
10
Half-sphere exposure sum ?
85
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q5QNS5
Residue number A
37
Residue number B
49
Peptide name
Hepatitis A virus cellular receptor 1 homolog

Ligandability

Cysteine 37 of Hepatitis A virus cellular receptor 1 homolog

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 49 of Hepatitis A virus cellular receptor 1 homolog

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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