ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

39S ribosomal protein L38, mitochondrial

Intramolecular
Cysteine 252 and cysteine 290 L
A redox-regulated disulphide may form within 39S ribosomal protein L38, mitochondrial between cysteines 252 and 290. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
56
PDB code
3j7y
Structure name
structure of the large ribosomal subunit from human mitochondria
Structure deposition date
2014-08-26
Thiol separation (Å)
8
Half-sphere exposure sum ?
48
Minimum pKa ?
9
% buried
24
Peptide accession
Q96DV4
Residue number A
252
Residue number B
290
Peptide name
39S ribosomal protein L38, mitochondrial

Ligandability

Cysteine 252 of 39S ribosomal protein L38, mitochondrial

Cysteine 290 of 39S ribosomal protein L38, mitochondrial

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