ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

39S ribosomal protein L53, mitochondrial

Intramolecular
Cysteine 21 and cysteine 63 L
A redox-regulated disulphide may form within 39S ribosomal protein L53, mitochondrial between cysteines 21 and 63. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
34
PDB code
7oia
Structure name
cryo-em structure of late human 39s mitoribosome assembly intermediates, state 3c
Structure deposition date
2021-05-11
Thiol separation (Å)
10
Half-sphere exposure sum ?
61
Minimum pKa ?
10
% buried
24
Peptide accession
Q96EL3
Residue number A
21
Residue number B
63
Peptide name
39S ribosomal protein L53, mitochondrial

Ligandability

Cysteine 21 of 39S ribosomal protein L53, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 63 of 39S ribosomal protein L53, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: