a tool for identifying drug-targetable redox-active disulphides

Chronophin

Intramolecular

Cysteine 91 and cysteine 221

A redox-regulated disulphide may form within Chronophin between cysteines 91 and 221.

Details

Redox score ?

70

PDB code

Structure name

crystal structure of human pyridoxal phosphate phosphatase

Structure deposition date

2007-02-21

Thiol separation (Å)

4

Half-sphere exposure sum ?

73

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

91

Residue number B

221

Peptide name

Chronophin

Ligandability

Cysteine 91 of Chronophin

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 221 of Chronophin

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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