a tool for identifying drug-targetable redox-active disulphides

Protein lin-37 homolog

Intermolecular

Cysteine 122 of Protein lin-9 homolog and cysteine 119

A redox-regulated disulphide may form between cysteine 122 of Protein lin-9 homolog and cysteine 119 of Protein lin-37 homolog.

Details

Redox score ?

66

PDB code

Structure name

crystal structure of lin9-rbap48-lin37, a muvb subcomplex

Structure deposition date

2021-06-02

Thiol separation (Å)

4

Half-sphere exposure sum ?

86

Minimum pK_a ?

9

% buried

100

Peptide A name

Protein lin-9 homolog

Peptide B name

Protein lin-37 homolog

Peptide A accession

Peptide B accession

Peptide A residue number

122

Peptide B residue number

119

Ligandability

Cysteine 122 of Protein lin-9 homolog

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 119 of Protein lin-37 homolog

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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