ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Centromere protein N

Intermolecular
Cysteine 286 of Centromere protein L and cysteine 293
A redox-regulated disulphide may form between cysteine 286 of Centromere protein L and cysteine 293 of Centromere protein N. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
33
PDB code
7yyh
Structure name
structure of the human ccandeltat cenp-a alpha-satellite complex
Structure deposition date
2022-02-17
Thiol separation (Å)
10
Half-sphere exposure sum ?
61
Minimum pKa ?
11
% buried
74
Peptide A name
Centromere protein L
Peptide B name
Centromere protein N
Peptide A accession
Q8N0S6
Peptide B accession
Q96H22
Peptide A residue number
286
Peptide B residue number
293

Ligandability

Cysteine 286 of Centromere protein L

Cysteine 293 of Centromere protein N

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