ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Transmembrane protein 141

Intramolecular
Cysteine 26 and cysteine 86
A redox-regulated disulphide may form within Transmembrane protein 141 between cysteines 26 and 86. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
56
PDB code
2lor
Structure name
backbone structure of human membrane protein tmem141
Structure deposition date
2012-01-26
Thiol separation (Å)
8
Half-sphere exposure sum ?
43
Minimum pKa ?
10
% buried
6
Peptide accession
Q96I45
Residue number A
26
Residue number B
86
Peptide name
Transmembrane protein 141

Ligandability

Cysteine 26 of Transmembrane protein 141

Cysteine 86 of Transmembrane protein 141

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