ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

Intramolecular
Cysteine 305 and cysteine 317
A redox-regulated disulphide may form within Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial between cysteines 305 and 317 (268 and 280 respectively in this structure).

Details

Redox score ?
66
PDB code
7mst
Structure name
phosphorylated human e105qa gtp-specific succinyl-coa synthetase complexed with coenzyme a
Structure deposition date
2021-05-12
Thiol separation (Å)
4
Half-sphere exposure sum ?
106
Minimum pKa ?
9
% buried
100
Peptide accession
Q96I99
Residue number A
305
Residue number B
317
Peptide name
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

Ligandability

Cysteine 305 of Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

Cysteine 317 of Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

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