ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Peptidoglycan recognition protein 4

Intramolecular
Cysteine 210 and cysteine 332
Cysteine 226 and cysteine 270
Cysteine 246 and cysteine 252
A redox-regulated disulphide may form within Peptidoglycan recognition protein 4 between cysteines 210 and 332.

Details

Redox score ?
89
PDB code
2eax
Structure name
crystal structure of human pgrp-ibetac in complex with glycosamyl muramyl pentapeptide
Structure deposition date
2007-02-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q3B822
Residue number A
210
Residue number B
332
Peptide name
Peptidoglycan recognition protein 4

Ligandability

Cysteine 210 of Peptidoglycan recognition protein 4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 332 of Peptidoglycan recognition protein 4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Peptidoglycan recognition protein 4 between cysteines 226 and 270.

Details

Redox score ?
85
PDB code
2eax
Structure name
crystal structure of human pgrp-ibetac in complex with glycosamyl muramyl pentapeptide
Structure deposition date
2007-02-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
45
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q3B822
Residue number A
226
Residue number B
270
Peptide name
Peptidoglycan recognition protein 4

Ligandability

Cysteine 226 of Peptidoglycan recognition protein 4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 270 of Peptidoglycan recognition protein 4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Peptidoglycan recognition protein 4 between cysteines 246 and 252.

Details

Redox score ?
84
PDB code
2eax
Structure name
crystal structure of human pgrp-ibetac in complex with glycosamyl muramyl pentapeptide
Structure deposition date
2007-02-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q3B822
Residue number A
246
Residue number B
252
Peptide name
Peptidoglycan recognition protein 4

Ligandability

Cysteine 246 of Peptidoglycan recognition protein 4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 252 of Peptidoglycan recognition protein 4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: