Kremen protein 1
Intramolecular
Cysteine 32 and cysteine 114
Cysteine 55 and cysteine 95
Cysteine 122 and cysteine 186
Cysteine 214 and cysteine 240
Cysteine 84 and cysteine 109
Cysteine 151 and cysteine 169
Cysteine 190 and cysteine 198
Cysteine 147 and cysteine 167
Cysteine 55 and cysteine 84
Cysteine 55 and cysteine 109
More...Cysteine 95 and cysteine 109
Cysteine 151 and cysteine 167
Cysteine 147 and cysteine 151
Cysteine 84 and cysteine 95
Cysteine 167 and cysteine 169
Cysteine 147 and cysteine 169
Cysteine 147 and cysteine 198
Cysteine 84 and cysteine 114
Cysteine 147 and cysteine 190
Cysteine 109 and cysteine 114
Cysteine 167 and cysteine 198
Cysteine 186 and cysteine 198
5fww B 32 B 114
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 32 and 114.
Details
Redox score ?
86
PDB code
5fww
Structure name
wnt modulator kremen in complex with dkk1 (crd2) and lrp6 (pe3pe4)
Structure deposition date
2016-02-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
32
Residue number B
114
Peptide name
Kremen protein 1
Ligandability
Cysteine 32 of Kremen protein 1
Cysteine 114 of Kremen protein 1
5fwv A 55 A 95
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 55 and 95.
Details
Redox score ?
83
PDB code
5fwv
Structure name
wnt modulator kremen crystal form iii at 3
Structure deposition date
2016-02-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
55
Residue number B
95
Peptide name
Kremen protein 1
Ligandability
Cysteine 55 of Kremen protein 1
Cysteine 95 of Kremen protein 1
5fwu A 122 A 186
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 122 and 186.
Details
Redox score ?
83
PDB code
5fwu
Structure name
wnt modulator kremen crystal form ii at 2
Structure deposition date
2016-02-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
79
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
122
Residue number B
186
Peptide name
Kremen protein 1
Ligandability
Cysteine 122 of Kremen protein 1
Cysteine 186 of Kremen protein 1
5fww B 214 B 240
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 214 and 240.
Details
Redox score ?
82
PDB code
5fww
Structure name
wnt modulator kremen in complex with dkk1 (crd2) and lrp6 (pe3pe4)
Structure deposition date
2016-02-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
214
Residue number B
240
Peptide name
Kremen protein 1
Ligandability
Cysteine 214 of Kremen protein 1
Cysteine 240 of Kremen protein 1
5fwv A 84 A 109
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 84 and 109.
Details
Redox score ?
82
PDB code
5fwv
Structure name
wnt modulator kremen crystal form iii at 3
Structure deposition date
2016-02-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
85
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
84
Residue number B
109
Peptide name
Kremen protein 1
Ligandability
Cysteine 84 of Kremen protein 1
Cysteine 109 of Kremen protein 1
5fwv A 151 A 169
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 151 and 169.
Details
Redox score ?
82
PDB code
5fwv
Structure name
wnt modulator kremen crystal form iii at 3
Structure deposition date
2016-02-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
151
Residue number B
169
Peptide name
Kremen protein 1
Ligandability
Cysteine 151 of Kremen protein 1
Cysteine 169 of Kremen protein 1
5fwt A 190 A 198
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 190 and 198.
Details
Redox score ?
80
PDB code
5fwt
Structure name
wnt modulator kremen crystal form i at 2
Structure deposition date
2016-02-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
94
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
190
Residue number B
198
Peptide name
Kremen protein 1
Ligandability
Cysteine 190 of Kremen protein 1
Cysteine 198 of Kremen protein 1
5fww B 147 B 167
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 147 and 167.
Details
Redox score ?
78
PDB code
5fww
Structure name
wnt modulator kremen in complex with dkk1 (crd2) and lrp6 (pe3pe4)
Structure deposition date
2016-02-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
95
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
147
Residue number B
167
Peptide name
Kremen protein 1
Ligandability
Cysteine 147 of Kremen protein 1
Cysteine 167 of Kremen protein 1
5fwu A 55 A 84
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 55 and 84.
Details
Redox score ?
74
PDB code
5fwu
Structure name
wnt modulator kremen crystal form ii at 2
Structure deposition date
2016-02-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
55
Residue number B
84
Peptide name
Kremen protein 1
Ligandability
Cysteine 55 of Kremen protein 1
Cysteine 84 of Kremen protein 1
5fws A 55 A 109
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 55 and 109.
Details
Redox score ?
72
PDB code
5fws
Structure name
wnt modulator kremen crystal form i at 1
Structure deposition date
2016-02-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
55
Residue number B
109
Peptide name
Kremen protein 1
Ligandability
Cysteine 55 of Kremen protein 1
Cysteine 109 of Kremen protein 1
5fwv A 95 A 109
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 95 and 109.
Details
Redox score ?
70
PDB code
5fwv
Structure name
wnt modulator kremen crystal form iii at 3
Structure deposition date
2016-02-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
85
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
95
Residue number B
109
Peptide name
Kremen protein 1
Ligandability
Cysteine 95 of Kremen protein 1
Cysteine 109 of Kremen protein 1
5fwu A 151 A 167
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 151 and 167.
Details
Redox score ?
69
PDB code
5fwu
Structure name
wnt modulator kremen crystal form ii at 2
Structure deposition date
2016-02-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
151
Residue number B
167
Peptide name
Kremen protein 1
Ligandability
Cysteine 151 of Kremen protein 1
Cysteine 167 of Kremen protein 1
5fwt A 147 A 151
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 147 and 151.
Details
Redox score ?
68
PDB code
5fwt
Structure name
wnt modulator kremen crystal form i at 2
Structure deposition date
2016-02-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
85
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
147
Residue number B
151
Peptide name
Kremen protein 1
Ligandability
Cysteine 147 of Kremen protein 1
Cysteine 151 of Kremen protein 1
5fwt A 84 A 95
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 84 and 95.
Details
Redox score ?
67
PDB code
5fwt
Structure name
wnt modulator kremen crystal form i at 2
Structure deposition date
2016-02-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
84
Residue number B
95
Peptide name
Kremen protein 1
Ligandability
Cysteine 84 of Kremen protein 1
Cysteine 95 of Kremen protein 1
5fws A 167 A 169
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 167 and 169.
Details
Redox score ?
65
PDB code
5fws
Structure name
wnt modulator kremen crystal form i at 1
Structure deposition date
2016-02-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
85
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
167
Residue number B
169
Peptide name
Kremen protein 1
Ligandability
Cysteine 167 of Kremen protein 1
Cysteine 169 of Kremen protein 1
5fwu A 147 A 169
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 147 and 169. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
57
PDB code
5fwu
Structure name
wnt modulator kremen crystal form ii at 2
Structure deposition date
2016-02-21
Thiol separation (Å)
6
Half-sphere exposure sum ?
89
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
147
Residue number B
169
Peptide name
Kremen protein 1
Ligandability
Cysteine 147 of Kremen protein 1
Cysteine 169 of Kremen protein 1
5fwu A 147 A 198
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 147 and 198. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
5fwu
Structure name
wnt modulator kremen crystal form ii at 2
Structure deposition date
2016-02-21
Thiol separation (Å)
7
Half-sphere exposure sum ?
100
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
147
Residue number B
198
Peptide name
Kremen protein 1
Ligandability
Cysteine 147 of Kremen protein 1
Cysteine 198 of Kremen protein 1
5fws A 84 A 114
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 84 and 114. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
5fws
Structure name
wnt modulator kremen crystal form i at 1
Structure deposition date
2016-02-21
Thiol separation (Å)
9
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
84
Residue number B
114
Peptide name
Kremen protein 1
Ligandability
Cysteine 84 of Kremen protein 1
Cysteine 114 of Kremen protein 1
5fwt A 147 A 190
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 147 and 190. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
5fwt
Structure name
wnt modulator kremen crystal form i at 2
Structure deposition date
2016-02-21
Thiol separation (Å)
9
Half-sphere exposure sum ?
90
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
147
Residue number B
190
Peptide name
Kremen protein 1
Ligandability
Cysteine 147 of Kremen protein 1
Cysteine 190 of Kremen protein 1
5fws A 109 A 114
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 109 and 114. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
5fws
Structure name
wnt modulator kremen crystal form i at 1
Structure deposition date
2016-02-21
Thiol separation (Å)
9
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
109
Residue number B
114
Peptide name
Kremen protein 1
Ligandability
Cysteine 109 of Kremen protein 1
Cysteine 114 of Kremen protein 1
5fww B 167 B 198
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 167 and 198. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
5fww
Structure name
wnt modulator kremen in complex with dkk1 (crd2) and lrp6 (pe3pe4)
Structure deposition date
2016-02-21
Thiol separation (Å)
9
Half-sphere exposure sum ?
98
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
167
Residue number B
198
Peptide name
Kremen protein 1
Ligandability
Cysteine 167 of Kremen protein 1
Cysteine 198 of Kremen protein 1
5fww B 186 B 198
A redox-regulated disulphide may form within Kremen protein 1 between cysteines 186 and 198. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
35
PDB code
5fww
Structure name
wnt modulator kremen in complex with dkk1 (crd2) and lrp6 (pe3pe4)
Structure deposition date
2016-02-21
Thiol separation (Å)
10
Half-sphere exposure sum ?
92
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96MU8
Residue number A
186
Residue number B
198
Peptide name
Kremen protein 1
Ligandability
Cysteine 186 of Kremen protein 1
Cysteine 198 of Kremen protein 1
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