Ankyrin repeat domain-containing protein 27
Intramolecular
Cysteine 717 and cysteine 720
Cysteine 711 and cysteine 720
Cysteine 711 and cysteine 717
Cysteine 715 and cysteine 717
Cysteine 715 and cysteine 720
Cysteine 711 and cysteine 715
Cysteine 504 and cysteine 544
Cysteine 504 and cysteine 556
Cysteine 504 and cysteine 537
Cysteine 537 and cysteine 556
Cysteine 785 and cysteine 818
6tl0 B 717 B 720
A redox-regulated disulphide may form within Ankyrin repeat domain-containing protein 27 between cysteines 717 and 720.
Details
Redox score ?
84
PDB code
6tl0
Structure name
solution structure and 1h, 13c and 15n chemical shift assignments for the complex of vps29 with varp 687-747
Structure deposition date
2019-11-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
36
Minimum pKa ?
9
% buried
6
Peptide accession
Q96NW4
Residue number A
717
Residue number B
720
Peptide name
Ankyrin repeat domain-containing protein 27
Ligandability
Cysteine 717 of Ankyrin repeat domain-containing protein 27
Cysteine 720 of Ankyrin repeat domain-containing protein 27
6tl0 B 711 B 720
A redox-regulated disulphide may form within Ankyrin repeat domain-containing protein 27 between cysteines 711 and 720.
Details
Redox score ?
81
PDB code
6tl0
Structure name
solution structure and 1h, 13c and 15n chemical shift assignments for the complex of vps29 with varp 687-747
Structure deposition date
2019-11-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
37
Minimum pKa ?
9
% buried
8
Peptide accession
Q96NW4
Residue number A
711
Residue number B
720
Peptide name
Ankyrin repeat domain-containing protein 27
Ligandability
Cysteine 711 of Ankyrin repeat domain-containing protein 27
Cysteine 720 of Ankyrin repeat domain-containing protein 27
6tl0 B 711 B 717
A redox-regulated disulphide may form within Ankyrin repeat domain-containing protein 27 between cysteines 711 and 717.
Details
Redox score ?
81
PDB code
6tl0
Structure name
solution structure and 1h, 13c and 15n chemical shift assignments for the complex of vps29 with varp 687-747
Structure deposition date
2019-11-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
39
Minimum pKa ?
9
% buried
4
Peptide accession
Q96NW4
Residue number A
711
Residue number B
717
Peptide name
Ankyrin repeat domain-containing protein 27
Ligandability
Cysteine 711 of Ankyrin repeat domain-containing protein 27
Cysteine 717 of Ankyrin repeat domain-containing protein 27
6tl0 B 715 B 717
A redox-regulated disulphide may form within Ankyrin repeat domain-containing protein 27 between cysteines 715 and 717.
Details
Redox score ?
81
PDB code
6tl0
Structure name
solution structure and 1h, 13c and 15n chemical shift assignments for the complex of vps29 with varp 687-747
Structure deposition date
2019-11-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
46
Minimum pKa ?
9
% buried
15
Peptide accession
Q96NW4
Residue number A
715
Residue number B
717
Peptide name
Ankyrin repeat domain-containing protein 27
Ligandability
Cysteine 715 of Ankyrin repeat domain-containing protein 27
Cysteine 717 of Ankyrin repeat domain-containing protein 27
6tl0 B 715 B 720
A redox-regulated disulphide may form within Ankyrin repeat domain-containing protein 27 between cysteines 715 and 720.
Details
Redox score ?
79
PDB code
6tl0
Structure name
solution structure and 1h, 13c and 15n chemical shift assignments for the complex of vps29 with varp 687-747
Structure deposition date
2019-11-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
44
Minimum pKa ?
9
% buried
18
Peptide accession
Q96NW4
Residue number A
715
Residue number B
720
Peptide name
Ankyrin repeat domain-containing protein 27
Ligandability
Cysteine 715 of Ankyrin repeat domain-containing protein 27
Cysteine 720 of Ankyrin repeat domain-containing protein 27
6tl0 B 711 B 715
A redox-regulated disulphide may form within Ankyrin repeat domain-containing protein 27 between cysteines 711 and 715.
Details
Redox score ?
78
PDB code
6tl0
Structure name
solution structure and 1h, 13c and 15n chemical shift assignments for the complex of vps29 with varp 687-747
Structure deposition date
2019-11-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
47
Minimum pKa ?
9
% buried
17
Peptide accession
Q96NW4
Residue number A
711
Residue number B
715
Peptide name
Ankyrin repeat domain-containing protein 27
Ligandability
Cysteine 711 of Ankyrin repeat domain-containing protein 27
Cysteine 715 of Ankyrin repeat domain-containing protein 27
4cym D 504 D 544
A redox-regulated disulphide may form within Ankyrin repeat domain-containing protein 27 between cysteines 504 and 544.
Details
Redox score ?
65
PDB code
4cym
Structure name
complex of human varp-ankrd1 with rab32-gppcp
Structure deposition date
2014-04-13
Thiol separation (Å)
5
Half-sphere exposure sum ?
88
Minimum pKa ?
8
% buried
91
Peptide accession
Q96NW4
Residue number A
504
Residue number B
544
Peptide name
Ankyrin repeat domain-containing protein 27
Ligandability
Cysteine 504 of Ankyrin repeat domain-containing protein 27
Cysteine 544 of Ankyrin repeat domain-containing protein 27
4cz2 D 504 D 556
A redox-regulated disulphide may form within Ankyrin repeat domain-containing protein 27 between cysteines 504 and 556. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
4cz2
Structure name
complex of human varp-ankrd1 with rab32-gppcp
Structure deposition date
2014-04-16
Thiol separation (Å)
9
Half-sphere exposure sum ?
73
Minimum pKa ?
8
% buried
96
Peptide accession
Q96NW4
Residue number A
504
Residue number B
556
Peptide name
Ankyrin repeat domain-containing protein 27
Ligandability
Cysteine 504 of Ankyrin repeat domain-containing protein 27
Cysteine 556 of Ankyrin repeat domain-containing protein 27
4cz2 E 504 E 537
A redox-regulated disulphide may form within Ankyrin repeat domain-containing protein 27 between cysteines 504 and 537. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
4cz2
Structure name
complex of human varp-ankrd1 with rab32-gppcp
Structure deposition date
2014-04-16
Thiol separation (Å)
9
Half-sphere exposure sum ?
85
Minimum pKa ?
9
% buried
100
Peptide accession
Q96NW4
Residue number A
504
Residue number B
537
Peptide name
Ankyrin repeat domain-containing protein 27
Ligandability
Cysteine 504 of Ankyrin repeat domain-containing protein 27
Cysteine 537 of Ankyrin repeat domain-containing protein 27
4cz2 F 537 F 556
A redox-regulated disulphide may form within Ankyrin repeat domain-containing protein 27 between cysteines 537 and 556. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
35
PDB code
4cz2
Structure name
complex of human varp-ankrd1 with rab32-gppcp
Structure deposition date
2014-04-16
Thiol separation (Å)
10
Half-sphere exposure sum ?
69
Minimum pKa ?
11
% buried
86
Peptide accession
Q96NW4
Residue number A
537
Residue number B
556
Peptide name
Ankyrin repeat domain-containing protein 27
Ligandability
Cysteine 537 of Ankyrin repeat domain-containing protein 27
Cysteine 556 of Ankyrin repeat domain-containing protein 27
4b93 B 785 B 818
A redox-regulated disulphide may form within Ankyrin repeat domain-containing protein 27 between cysteines 785 and 818. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
31
PDB code
4b93
Structure name
complex of vamp7 cytoplasmic domain with 2nd ankyrin repeat domain of varp
Structure deposition date
2012-08-31
Thiol separation (Å)
9
Half-sphere exposure sum ?
85
Minimum pKa ?
13
% buried
100
Peptide accession
Q96NW4
Residue number A
785
Residue number B
818
Peptide name
Ankyrin repeat domain-containing protein 27
Ligandability
Cysteine 785 of Ankyrin repeat domain-containing protein 27
Cysteine 818 of Ankyrin repeat domain-containing protein 27
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