Calcium/calmodulin-dependent protein kinase type 1G

Intermolecular

Intramolecular

A redox-regulated disulphide may form between two units of Calcium/calmodulin-dependent protein kinase type 1G at cysteines 214 and 180 (215 and 181 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

2jam

Structure name

crystal structure of human calmodulin-dependent protein kinase i g

Structure deposition date

2006-11-29

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide A name

Calcium/calmodulin-dependent protein kinase type 1G

Peptide B name

Calcium/calmodulin-dependent protein kinase type 1G

Peptide A accession

Q96NX5

Peptide B accession

Q96NX5

Peptide A residue number

214

Peptide B residue number

180

Ligandability

Cysteine 214 of Calcium/calmodulin-dependent protein kinase type 1G

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 180 of Calcium/calmodulin-dependent protein kinase type 1G

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Calcium/calmodulin-dependent protein kinase type 1G between cysteines 202 and 268 (203 and 269 respectively in this structure).