ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Crossover junction endonuclease MUS81

Intramolecular
Cysteine 510 and cysteine 545
A redox-regulated disulphide may form within Crossover junction endonuclease MUS81 between cysteines 510 and 545. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
51
PDB code
4p0s
Structure name
human mus81-eme1-3'flap dna complex
Structure deposition date
2014-02-22
Thiol separation (Å)
8
Half-sphere exposure sum ?
55
Minimum pKa ?
11
% buried
29
Peptide accession
Q96NY9
Residue number A
510
Residue number B
545
Peptide name
Crossover junction endonuclease MUS81

Ligandability

Cysteine 510 of Crossover junction endonuclease MUS81

Cysteine 545 of Crossover junction endonuclease MUS81

If this tool was useful for finding a disulphide, please cite: