ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Guanylate-binding protein 5

Intramolecular
Cysteine 184 and cysteine 233
A redox-regulated disulphide may form within Guanylate-binding protein 5 between cysteines 184 and 233. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
48
PDB code
7e59
Structure name
interferon-inducible anti-viral protein truncated
Structure deposition date
2021-02-18
Thiol separation (Å)
9
Half-sphere exposure sum ?
54
Minimum pKa ?
10
% buried
44
Peptide accession
Q96PP8
Residue number A
184
Residue number B
233
Peptide name
Guanylate-binding protein 5

Ligandability

Cysteine 184 of Guanylate-binding protein 5

Cysteine 233 of Guanylate-binding protein 5

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