ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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CUB and sushi domain-containing protein 1

Intramolecular
Cysteine 553 and cysteine 580
Cysteine 527 and cysteine 567
A redox-regulated disulphide may form within CUB and sushi domain-containing protein 1 between cysteines 553 and 580 (40 and 67 respectively in this structure).

Details

Redox score ?
88
PDB code
2ehf
Structure name
solution structure of the third sushi domain from human cub and sushi domain-containing protein 1
Structure deposition date
2007-03-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96PZ7
Residue number A
553
Residue number B
580
Peptide name
CUB and sushi domain-containing protein 1

Ligandability

Cysteine 553 of CUB and sushi domain-containing protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 580 of CUB and sushi domain-containing protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within CUB and sushi domain-containing protein 1 between cysteines 527 and 567 (14 and 54 respectively in this structure).

Details

Redox score ?
88
PDB code
2ehf
Structure name
solution structure of the third sushi domain from human cub and sushi domain-containing protein 1
Structure deposition date
2007-03-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q96PZ7
Residue number A
527
Residue number B
567
Peptide name
CUB and sushi domain-containing protein 1

Ligandability

Cysteine 527 of CUB and sushi domain-containing protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 567 of CUB and sushi domain-containing protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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