ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Calcium and integrin-binding family member 3

Intramolecular
Cysteine 124 and cysteine 149
A redox-regulated disulphide may form within Calcium and integrin-binding family member 3 between cysteines 124 and 149. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
40
PDB code
6wud
Structure name
human calcium and integrin binding protein 3 bound to tmc1 residues 303-347
Structure deposition date
2020-05-04
Thiol separation (Å)
9
Half-sphere exposure sum ?
70
Minimum pKa ?
8
% buried
50
Peptide accession
Q96Q77
Residue number A
124
Residue number B
149
Peptide name
Calcium and integrin-binding family member 3

Ligandability

Cysteine 124 of Calcium and integrin-binding family member 3

Cysteine 149 of Calcium and integrin-binding family member 3

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