a tool for identifying drug-targetable redox-active disulphides

MHC class I chain-related protein A

Intramolecular

Cysteine 225 and cysteine 282

A redox-regulated disulphide may form within MHC class I chain-related protein A between cysteines 225 and 282.

Details

Redox score ?

80

PDB code

Structure name

crystal structure analysis of the epitope of an anti-mica antibody

Structure deposition date

2018-05-10

Thiol separation (Å)

2

Half-sphere exposure sum ?

84

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

225

Residue number B

282

Peptide name

MHC class I chain-related protein A

Ligandability

Cysteine 225 of MHC class I chain-related protein A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 282 of MHC class I chain-related protein A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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