Transient receptor potential cation channel subfamily M member 7
Intermolecular
Cysteine 1606 and cysteine 1606
Intramolecular
Cysteine 1810 and cysteine 1814
Cysteine 1813 and cysteine 1814
Cysteine 1606 and cysteine 1629
1iaj A 1606 B 1606
A redox-regulated disulphide may form between two units of Transient receptor potential cation channel subfamily M member 7 at cysteines 1606 and 1606. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
34
PDB code
1iaj
Structure name
crystal structure of the atypical protein kinase domain of a trp ca-channel, chak (apo)
Structure deposition date
2001-03-22
Thiol separation (Å)
9
Half-sphere exposure sum ?
78
Minimum pKa ?
10
% buried
80
Peptide A name
Transient receptor potential cation channel subfamily M member 7
Peptide B name
Transient receptor potential cation channel subfamily M member 7
Peptide A accession
Q923J1
Peptide B accession
Q923J1
Peptide A residue number
1606
Peptide B residue number
1606
Ligandability
1iaj A 1810 A 1814
A redox-regulated disulphide may form within Transient receptor potential cation channel subfamily M member 7 between cysteines 1810 and 1814.
Details
Redox score ?
90
PDB code
1iaj
Structure name
crystal structure of the atypical protein kinase domain of a trp ca-channel, chak (apo)
Structure deposition date
2001-03-22
Thiol separation (Å)
4
Half-sphere exposure sum ?
66
Minimum pKa ?
1
% buried
59
Peptide accession
Q923J1
Residue number A
1810
Residue number B
1814
Peptide name
Transient receptor potential cation channel subfamily M member 7
Ligandability
Cysteine 1810 of Transient receptor potential cation channel subfamily M member 7
Cysteine 1814 of Transient receptor potential cation channel subfamily M member 7
1ia9 A 1813 A 1814
A redox-regulated disulphide may form within Transient receptor potential cation channel subfamily M member 7 between cysteines 1813 and 1814. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
1ia9
Structure name
crystal structure of the atypical protein kinase domain of a trp ca-channel, chak (amppnp complex)
Structure deposition date
2001-03-22
Thiol separation (Å)
6
Half-sphere exposure sum ?
62
Minimum pKa ?
11
% buried
74
Peptide accession
Q923J1
Residue number A
1813
Residue number B
1814
Peptide name
Transient receptor potential cation channel subfamily M member 7
Ligandability
Cysteine 1813 of Transient receptor potential cation channel subfamily M member 7
Cysteine 1814 of Transient receptor potential cation channel subfamily M member 7
1ia9 A 1606 A 1629
A redox-regulated disulphide may form within Transient receptor potential cation channel subfamily M member 7 between cysteines 1606 and 1629. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
34
PDB code
1ia9
Structure name
crystal structure of the atypical protein kinase domain of a trp ca-channel, chak (amppnp complex)
Structure deposition date
2001-03-22
Thiol separation (Å)
9
Half-sphere exposure sum ?
76
Minimum pKa ?
11
% buried
83
Peptide accession
Q923J1
Residue number A
1606
Residue number B
1629
Peptide name
Transient receptor potential cation channel subfamily M member 7
Ligandability
Cysteine 1606 of Transient receptor potential cation channel subfamily M member 7
Cysteine 1629 of Transient receptor potential cation channel subfamily M member 7
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