Bardet-Biedl syndrome 4 protein homolog

Intramolecular

A redox-regulated disulphide may form within Bardet-Biedl syndrome 4 protein homolog between cysteines 93 and 100. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

6vbv

Structure name

structure of the bovine bbsome:arl6:gtp complex

Structure deposition date

2019-12-19

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

Q1JQ97

Residue number A

Residue number B

100

Peptide name

Bardet-Biedl syndrome 4 protein homolog

Ligandability

Cysteine 93 of Bardet-Biedl syndrome 4 protein homolog

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 100 of Bardet-Biedl syndrome 4 protein homolog

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Bardet-Biedl syndrome 4 protein homolog between cysteines 66 and 93. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

6vnw

Structure name

cryo-em structure of apo-bbsome

Structure deposition date

2020-01-29

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

Q1JQ97

Residue number A

Residue number B

Peptide name

Bardet-Biedl syndrome 4 protein homolog

Ligandability

Cysteine 66 of Bardet-Biedl syndrome 4 protein homolog

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 93 of Bardet-Biedl syndrome 4 protein homolog

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Bardet-Biedl syndrome 4 protein homolog between cysteines 279 and 292. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?