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GATOR complex protein WDR24

Intramolecular
Cysteine 733 and cysteine 736
Cysteine 722 and cysteine 733
Cysteine 757 and cysteine 787
Cysteine 757 and cysteine 760
Cysteine 722 and cysteine 736
Cysteine 719 and cysteine 722
Cysteine 719 and cysteine 736
Cysteine 719 and cysteine 733
Cysteine 779 and cysteine 783
Cysteine 760 and cysteine 783
More...
Cysteine 757 and cysteine 779
Cysteine 783 and cysteine 787
Cysteine 760 and cysteine 787
Cysteine 757 and cysteine 783
Cysteine 743 and cysteine 746
Cysteine 779 and cysteine 787
Cysteine 430 and cysteine 457
Cysteine 23 and cysteine 324
Cysteine 212 and cysteine 213
Cysteine 760 and cysteine 779
Cysteine 212 and cysteine 270
Cysteine 127 and cysteine 213
A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 733 and 736.

Details

Redox score ?
93
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
3
Half-sphere exposure sum ?
50
Minimum pKa ?
6
% buried
2
Peptide accession
Q96S15
Residue number A
733
Residue number B
736
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 733 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 736 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 722 and 733.

Details

Redox score ?
91
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
3
Half-sphere exposure sum ?
50
Minimum pKa ?
6
% buried
2
Peptide accession
Q96S15
Residue number A
722
Residue number B
733
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 722 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 733 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 757 and 787.

Details

Redox score ?
89
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
4
Half-sphere exposure sum ?
83
Minimum pKa ?
0
% buried
80
Peptide accession
Q96S15
Residue number A
757
Residue number B
787
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 757 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 787 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 757 and 760.

Details

Redox score ?
89
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
4
Half-sphere exposure sum ?
76
Minimum pKa ?
0
% buried
80
Peptide accession
Q96S15
Residue number A
757
Residue number B
760
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 757 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 760 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 722 and 736.

Details

Redox score ?
86
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
3
Half-sphere exposure sum ?
40
Minimum pKa ?
9
% buried
0
Peptide accession
Q96S15
Residue number A
722
Residue number B
736
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 722 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 736 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 719 and 722.

Details

Redox score ?
82
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
4
Half-sphere exposure sum ?
53
Minimum pKa ?
7
% buried
14
Peptide accession
Q96S15
Residue number A
719
Residue number B
722
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 719 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 722 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 719 and 736.

Details

Redox score ?
82
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
4
Half-sphere exposure sum ?
53
Minimum pKa ?
7
% buried
14
Peptide accession
Q96S15
Residue number A
719
Residue number B
736
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 719 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 736 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 719 and 733.

Details

Redox score ?
81
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
5
Half-sphere exposure sum ?
63
Minimum pKa ?
6
% buried
15
Peptide accession
Q96S15
Residue number A
719
Residue number B
733
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 719 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 733 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 779 and 783.

Details

Redox score ?
79
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
3
Half-sphere exposure sum ?
69
Minimum pKa ?
7
% buried
nan
Peptide accession
Q96S15
Residue number A
779
Residue number B
783
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 779 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 783 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 760 and 783.

Details

Redox score ?
75
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
7
% buried
65
Peptide accession
Q96S15
Residue number A
760
Residue number B
783
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 760 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 783 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 757 and 779.

Details

Redox score ?
72
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
7
Half-sphere exposure sum ?
83
Minimum pKa ?
0
% buried
nan
Peptide accession
Q96S15
Residue number A
757
Residue number B
779
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 757 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 779 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 783 and 787.

Details

Redox score ?
69
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
5
Half-sphere exposure sum ?
68
Minimum pKa ?
7
% buried
64
Peptide accession
Q96S15
Residue number A
783
Residue number B
787
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 783 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 787 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 760 and 787.

Details

Redox score ?
66
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
3
Half-sphere exposure sum ?
67
Minimum pKa ?
15
% buried
76
Peptide accession
Q96S15
Residue number A
760
Residue number B
787
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 760 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 787 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 757 and 783.

Details

Redox score ?
66
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
8
Half-sphere exposure sum ?
78
Minimum pKa ?
0
% buried
70
Peptide accession
Q96S15
Residue number A
757
Residue number B
783
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 757 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 783 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 743 and 746.

Details

Redox score ?
62
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
4
Half-sphere exposure sum ?
67
Minimum pKa ?
14
% buried
nan
Peptide accession
Q96S15
Residue number A
743
Residue number B
746
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 743 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 746 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 779 and 787. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
58
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
4
Half-sphere exposure sum ?
74
Minimum pKa ?
15
% buried
nan
Peptide accession
Q96S15
Residue number A
779
Residue number B
787
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 779 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 787 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 430 and 457. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
56
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
8
Half-sphere exposure sum ?
54
Minimum pKa ?
9
% buried
28
Peptide accession
Q96S15
Residue number A
430
Residue number B
457
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 430 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 457 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 23 and 324. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
46
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
8
Half-sphere exposure sum ?
68
Minimum pKa ?
10
% buried
46
Peptide accession
Q96S15
Residue number A
23
Residue number B
324
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 23 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 324 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 212 and 213. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
40
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
7
Half-sphere exposure sum ?
87
Minimum pKa ?
12
% buried
100
Peptide accession
Q96S15
Residue number A
212
Residue number B
213
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 212 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 213 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 760 and 779. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
37
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
4
Half-sphere exposure sum ?
67
Minimum pKa ?
26
% buried
nan
Peptide accession
Q96S15
Residue number A
760
Residue number B
779
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 760 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 779 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 212 and 270. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
35
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
8
Half-sphere exposure sum ?
88
Minimum pKa ?
11
% buried
100
Peptide accession
Q96S15
Residue number A
212
Residue number B
270
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 212 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 270 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within GATOR complex protein WDR24 between cysteines 127 and 213. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
34
PDB code
7uhy
Structure name
human gator2 complex
Structure deposition date
2022-03-27
Thiol separation (Å)
9
Half-sphere exposure sum ?
83
Minimum pKa ?
10
% buried
100
Peptide accession
Q96S15
Residue number A
127
Residue number B
213
Peptide name
GATOR complex protein WDR24

Ligandability

Cysteine 127 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 213 of GATOR complex protein WDR24

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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