ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Zinc finger protein 347

Intramolecular
Cysteine 683 and cysteine 686
Cysteine 711 and cysteine 714
Cysteine 319 and cysteine 322
Cysteine 543 and cysteine 546
Cysteine 347 and cysteine 378
Cysteine 291 and cysteine 294
Cysteine 347 and cysteine 602
Cysteine 459 and cysteine 462
Cysteine 347 and cysteine 350
A redox-regulated disulphide may form within Zinc finger protein 347 between cysteines 683 and 686.

Details

Redox score ?
89
PDB code
2eq2
Structure name
solution structure of the 16th c2h2 type zinc finger domain of zinc finger protein 347
Structure deposition date
2007-03-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
34
Minimum pKa ?
6
% buried
0
Peptide accession
Q96SE7
Residue number A
683
Residue number B
686
Peptide name
Zinc finger protein 347

Ligandability

Cysteine 683 of Zinc finger protein 347

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 686 of Zinc finger protein 347

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger protein 347 between cysteines 711 and 714.

Details

Redox score ?
88
PDB code
2eq3
Structure name
solution structure of the 17th c2h2 type zinc finger domain of zinc finger protein 347
Structure deposition date
2007-03-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
34
Minimum pKa ?
6
% buried
0
Peptide accession
Q96SE7
Residue number A
711
Residue number B
714
Peptide name
Zinc finger protein 347

Ligandability

Cysteine 711 of Zinc finger protein 347

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 714 of Zinc finger protein 347

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger protein 347 between cysteines 319 and 322 (15 and 18 respectively in this structure).

Details

Redox score ?
87
PDB code
2ema
Structure name
solution structure of the c2h2 type zinc finger (region 312-344) of human zinc finger protein 347
Structure deposition date
2007-03-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
36
Minimum pKa ?
7
% buried
0
Peptide accession
Q96SE7
Residue number A
319
Residue number B
322
Peptide name
Zinc finger protein 347

Ligandability

Cysteine 319 of Zinc finger protein 347

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 322 of Zinc finger protein 347

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger protein 347 between cysteines 543 and 546 (15 and 18 respectively in this structure).

Details

Redox score ?
86
PDB code
2emp
Structure name
solution structure of the c2h2 type zinc finger (region 536-568) of human zinc finger protein 347
Structure deposition date
2007-03-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
40
Minimum pKa ?
7
% buried
0
Peptide accession
Q96SE7
Residue number A
543
Residue number B
546
Peptide name
Zinc finger protein 347

Ligandability

Cysteine 543 of Zinc finger protein 347

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 546 of Zinc finger protein 347

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger protein 347 between cysteines 347 and 378 (15 and 18 respectively in this structure).

Details

Redox score ?
86
PDB code
2eow
Structure name
solution structure of the c2h2 type zinc finger (region 368-400) of human zinc finger protein 347
Structure deposition date
2007-03-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
35
Minimum pKa ?
7
% buried
0
Peptide accession
Q96SE7
Residue number A
347
Residue number B
378
Peptide name
Zinc finger protein 347

Ligandability

Cysteine 347 of Zinc finger protein 347

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 378 of Zinc finger protein 347

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger protein 347 between cysteines 291 and 294 (15 and 18 respectively in this structure).

Details

Redox score ?
85
PDB code
2en4
Structure name
solution structure of the c2h2 type zinc finger (region 284-316) of human zinc finger protein 347
Structure deposition date
2007-03-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
39
Minimum pKa ?
7
% buried
0
Peptide accession
Q96SE7
Residue number A
291
Residue number B
294
Peptide name
Zinc finger protein 347

Ligandability

Cysteine 291 of Zinc finger protein 347

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 294 of Zinc finger protein 347

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger protein 347 between cysteines 347 and 602 (15 and 18 respectively in this structure).

Details

Redox score ?
84
PDB code
2ene
Structure name
solution structure of the c2h2 type zinc finger (region 592-624) of human zinc finger protein 347
Structure deposition date
2007-03-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
49
Minimum pKa ?
7
% buried
0
Peptide accession
Q96SE7
Residue number A
347
Residue number B
602
Peptide name
Zinc finger protein 347

Ligandability

Cysteine 347 of Zinc finger protein 347

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 602 of Zinc finger protein 347

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger protein 347 between cysteines 459 and 462.

Details

Redox score ?
84
PDB code
2eq0
Structure name
solution structure of the 8th c2h2 type zinc finger domain of zinc finger protein 347
Structure deposition date
2007-03-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
36
Minimum pKa ?
8
% buried
0
Peptide accession
Q96SE7
Residue number A
459
Residue number B
462
Peptide name
Zinc finger protein 347

Ligandability

Cysteine 459 of Zinc finger protein 347

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 462 of Zinc finger protein 347

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger protein 347 between cysteines 347 and 350 (15 and 18 respectively in this structure).

Details

Redox score ?
84
PDB code
2enf
Structure name
solution structure of the c2h2 type zinc finger (region 340-372) of human zinc finger protein 347
Structure deposition date
2007-03-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
40
Minimum pKa ?
7
% buried
0
Peptide accession
Q96SE7
Residue number A
347
Residue number B
350
Peptide name
Zinc finger protein 347

Ligandability

Cysteine 347 of Zinc finger protein 347

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 350 of Zinc finger protein 347

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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