MMS19 nucleotide excision repair protein homolog
Intramolecular
Cysteine 724 and cysteine 761 L
Cysteine 287 and cysteine 332
Cysteine 332 and cysteine 335
Cysteine 286 and cysteine 287
Cysteine 836 and cysteine 925
Cysteine 600 and cysteine 627
Cysteine 582 and cysteine 627
Cysteine 937 and cysteine 978
Cysteine 286 and cysteine 332
6tc0 C 724 C 761
A redox-regulated disulphide may form within MMS19 nucleotide excision repair protein homolog between cysteines 724 and 761.
Details
Redox score ?
65
PDB code
6tc0
Structure name
crystal structure of mms19-ciao1-ciao2b cia targeting complex
Structure deposition date
2019-11-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
90
Minimum pKa ?
8
% buried
100
Peptide accession
Q9D071
Residue number A
724
Residue number B
761
Peptide name
MMS19 nucleotide excision repair protein homolog
Ligandability
Cysteine 724 of MMS19 nucleotide excision repair protein homolog
Cysteine 761 of MMS19 nucleotide excision repair protein homolog
6tc0 C 287 C 332
A redox-regulated disulphide may form within MMS19 nucleotide excision repair protein homolog between cysteines 287 and 332. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
58
PDB code
6tc0
Structure name
crystal structure of mms19-ciao1-ciao2b cia targeting complex
Structure deposition date
2019-11-04
Thiol separation (Å)
5
Half-sphere exposure sum ?
70
Minimum pKa ?
11
% buried
70
Peptide accession
Q9D071
Residue number A
287
Residue number B
332
Peptide name
MMS19 nucleotide excision repair protein homolog
Ligandability
Cysteine 287 of MMS19 nucleotide excision repair protein homolog
Cysteine 332 of MMS19 nucleotide excision repair protein homolog
6tc0 F 332 F 335
A redox-regulated disulphide may form within MMS19 nucleotide excision repair protein homolog between cysteines 332 and 335. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
6tc0
Structure name
crystal structure of mms19-ciao1-ciao2b cia targeting complex
Structure deposition date
2019-11-04
Thiol separation (Å)
7
Half-sphere exposure sum ?
60
Minimum pKa ?
9
% buried
28
Peptide accession
Q9D071
Residue number A
332
Residue number B
335
Peptide name
MMS19 nucleotide excision repair protein homolog
Ligandability
Cysteine 332 of MMS19 nucleotide excision repair protein homolog
Cysteine 335 of MMS19 nucleotide excision repair protein homolog
6tc0 C 286 C 287
A redox-regulated disulphide may form within MMS19 nucleotide excision repair protein homolog between cysteines 286 and 287. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
6tc0
Structure name
crystal structure of mms19-ciao1-ciao2b cia targeting complex
Structure deposition date
2019-11-04
Thiol separation (Å)
7
Half-sphere exposure sum ?
67
Minimum pKa ?
12
% buried
91
Peptide accession
Q9D071
Residue number A
286
Residue number B
287
Peptide name
MMS19 nucleotide excision repair protein homolog
Ligandability
Cysteine 286 of MMS19 nucleotide excision repair protein homolog
Cysteine 287 of MMS19 nucleotide excision repair protein homolog
6tc0 C 836 C 925
A redox-regulated disulphide may form within MMS19 nucleotide excision repair protein homolog between cysteines 836 and 925. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
6tc0
Structure name
crystal structure of mms19-ciao1-ciao2b cia targeting complex
Structure deposition date
2019-11-04
Thiol separation (Å)
9
Half-sphere exposure sum ?
56
Minimum pKa ?
9
% buried
28
Peptide accession
Q9D071
Residue number A
836
Residue number B
925
Peptide name
MMS19 nucleotide excision repair protein homolog
Ligandability
Cysteine 836 of MMS19 nucleotide excision repair protein homolog
Cysteine 925 of MMS19 nucleotide excision repair protein homolog
6tc0 C 600 C 627
A redox-regulated disulphide may form within MMS19 nucleotide excision repair protein homolog between cysteines 600 and 627. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
6tc0
Structure name
crystal structure of mms19-ciao1-ciao2b cia targeting complex
Structure deposition date
2019-11-04
Thiol separation (Å)
7
Half-sphere exposure sum ?
75
Minimum pKa ?
12
% buried
95
Peptide accession
Q9D071
Residue number A
600
Residue number B
627
Peptide name
MMS19 nucleotide excision repair protein homolog
Ligandability
Cysteine 600 of MMS19 nucleotide excision repair protein homolog
Cysteine 627 of MMS19 nucleotide excision repair protein homolog
6tc0 C 582 C 627
A redox-regulated disulphide may form within MMS19 nucleotide excision repair protein homolog between cysteines 582 and 627. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
6tc0
Structure name
crystal structure of mms19-ciao1-ciao2b cia targeting complex
Structure deposition date
2019-11-04
Thiol separation (Å)
9
Half-sphere exposure sum ?
62
Minimum pKa ?
10
% buried
76
Peptide accession
Q9D071
Residue number A
582
Residue number B
627
Peptide name
MMS19 nucleotide excision repair protein homolog
Ligandability
Cysteine 582 of MMS19 nucleotide excision repair protein homolog
Cysteine 627 of MMS19 nucleotide excision repair protein homolog
6tbl A 937 A 978
A redox-regulated disulphide may form within MMS19 nucleotide excision repair protein homolog between cysteines 937 and 978. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
35
PDB code
6tbl
Structure name
crystal structure of mms19(ctd)-ciao1-ciao2b cia targeting complex
Structure deposition date
2019-11-01
Thiol separation (Å)
10
Half-sphere exposure sum ?
68
Minimum pKa ?
9
% buried
44
Peptide accession
Q9D071
Residue number A
937
Residue number B
978
Peptide name
MMS19 nucleotide excision repair protein homolog
Ligandability
Cysteine 937 of MMS19 nucleotide excision repair protein homolog
Cysteine 978 of MMS19 nucleotide excision repair protein homolog
6tc0 C 286 C 332
A redox-regulated disulphide may form within MMS19 nucleotide excision repair protein homolog between cysteines 286 and 332. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
32
PDB code
6tc0
Structure name
crystal structure of mms19-ciao1-ciao2b cia targeting complex
Structure deposition date
2019-11-04
Thiol separation (Å)
10
Half-sphere exposure sum ?
69
Minimum pKa ?
11
% buried
71
Peptide accession
Q9D071
Residue number A
286
Residue number B
332
Peptide name
MMS19 nucleotide excision repair protein homolog
Ligandability
Cysteine 286 of MMS19 nucleotide excision repair protein homolog
Cysteine 332 of MMS19 nucleotide excision repair protein homolog
If this tool was useful for finding a disulphide, please cite: