ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Regulator of microtubule dynamics protein 3

Intramolecular
Cysteine 373 and cysteine 427
A redox-regulated disulphide may form within Regulator of microtubule dynamics protein 3 between cysteines 373 and 427. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
35
PDB code
7cc7
Structure name
tetratricopeptide repeat (tpr) domain of protein tyrosine phosphatase- interacting protein 51 (ptpip51)
Structure deposition date
2020-06-16
Thiol separation (Å)
9
Half-sphere exposure sum ?
70
Minimum pKa ?
12
% buried
71
Peptide accession
Q96TC7
Residue number A
373
Residue number B
427
Peptide name
Regulator of microtubule dynamics protein 3

Ligandability

Cysteine 373 of Regulator of microtubule dynamics protein 3

Cysteine 427 of Regulator of microtubule dynamics protein 3

If this tool was useful for finding a disulphide, please cite: