ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

Intramolecular
Cysteine 536 and cysteine 542
A redox-regulated disulphide may form within Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 between cysteines 536 and 542 (200 and 206 respectively in this structure).

Details

Redox score ?
78
PDB code
2bmj
Structure name
gtpase like domain of centaurin gamma 1 (human)
Structure deposition date
2005-03-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
58
Minimum pKa ?
10
% buried
50
Peptide accession
Q99490
Residue number A
536
Residue number B
542
Peptide name
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

Ligandability

Cysteine 536 of Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

Cysteine 542 of Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

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