Parkinson disease protein 7

Intermolecular

A redox-regulated disulphide is known to form between two units of Parkinson disease protein 7 at cysteines 53 and 53 (3053 and 3253 respectively in this structure).

Details

Redox score ?

PDB code

1pdw

Structure name

crystal structure of human dj-1, p 1 21 1 space group

Structure deposition date

2003-05-20

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide A name

Parkinson disease protein 7

Peptide B name

Parkinson disease protein 7

Peptide A accession

Q99497

Peptide B accession

Q99497

Peptide A residue number

Peptide B residue number

Ligandability

Cysteine 53 of Parkinson disease protein 7

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 53 of Parkinson disease protein 7

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form between two units of Parkinson disease protein 7 at cysteines 46 and 53 (446 and 653 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?