ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Synaptic vesicle membrane protein VAT-1 homolog

Intermolecular
Cysteine 324 and cysteine 324
A redox-regulated disulphide may form between two units of Synaptic vesicle membrane protein VAT-1 homolog at cysteines 324 and 324. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
45
PDB code
6lii
Structure name
a quinone oxidoreductase
Structure deposition date
2019-12-11
Thiol separation (Å)
6
Half-sphere exposure sum ?
109
Minimum pKa ?
12
% buried
100
Peptide A name
Synaptic vesicle membrane protein VAT-1 homolog
Peptide B name
Synaptic vesicle membrane protein VAT-1 homolog
Peptide A accession
Q99536
Peptide B accession
Q99536
Peptide A residue number
324
Peptide B residue number
324

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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