Eukaryotic translation initiation factor 3 subunit C

Intermolecular

Cysteine 443 and cysteine 59 of 40S ribosomal protein S27

A redox-regulated disulphide may form between cysteine 443 of Eukaryotic translation initiation factor 3 subunit C and cysteine 59 of 40S ribosomal protein S27.

Details

Redox score ?

PDB code

6ybd

Structure name

structure of a human 48s translational initiation complex - eif3

Structure deposition date

2020-03-16

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide A name

Eukaryotic translation initiation factor 3 subunit C

Peptide B name

40S ribosomal protein S27

Peptide A accession

Q99613

Peptide B accession

P42677

Peptide A residue number

443

Peptide B residue number

Ligandability

Cysteine 443 of Eukaryotic translation initiation factor 3 subunit C

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.