C-C motif chemokine 13
Intermolecular
Cysteine 34 and cysteine 34
Cysteine 34 and cysteine 58
Cysteine 58 and cysteine 58
Intramolecular
Cysteine 35 and cysteine 74
Cysteine 35 and cysteine 58
Cysteine 34 and cysteine 35
Cysteine 58 and cysteine 74
Cysteine 34 and cysteine 74
2ra4 A 11 B 11
A redox-regulated disulphide may form between two units of C-C motif chemokine 13 at cysteines 34 and 34 (11 and 11 respectively in this structure).
Details
Redox score ?
65
PDB code
2ra4
Structure name
crystal structure of human monocyte chemoattractant protein 4 (mcp- 4/ccl13)
Structure deposition date
2007-09-14
Thiol separation (Å)
5
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C motif chemokine 13
Peptide B name
C-C motif chemokine 13
Peptide A accession
Q99616
Peptide B accession
Q99616
Peptide A residue number
34
Peptide B residue number
34
Ligandability
2ra4 A 11 B 35
A redox-regulated disulphide may form between two units of C-C motif chemokine 13 at cysteines 34 and 58 (11 and 35 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
58
PDB code
2ra4
Structure name
crystal structure of human monocyte chemoattractant protein 4 (mcp- 4/ccl13)
Structure deposition date
2007-09-14
Thiol separation (Å)
7
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C motif chemokine 13
Peptide B name
C-C motif chemokine 13
Peptide A accession
Q99616
Peptide B accession
Q99616
Peptide A residue number
34
Peptide B residue number
58
Ligandability
Cysteine 34 of C-C motif chemokine 13
Cysteine 58 of C-C motif chemokine 13
2ra4 A 35 B 35
A redox-regulated disulphide may form between two units of C-C motif chemokine 13 at cysteines 58 and 58 (35 and 35 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
2ra4
Structure name
crystal structure of human monocyte chemoattractant protein 4 (mcp- 4/ccl13)
Structure deposition date
2007-09-14
Thiol separation (Å)
9
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C motif chemokine 13
Peptide B name
C-C motif chemokine 13
Peptide A accession
Q99616
Peptide B accession
Q99616
Peptide A residue number
58
Peptide B residue number
58
Ligandability
2ra4 B 12 B 51
A redox-regulated disulphide may form within C-C motif chemokine 13 between cysteines 35 and 74 (12 and 51 respectively in this structure).
Details
Redox score ?
80
PDB code
2ra4
Structure name
crystal structure of human monocyte chemoattractant protein 4 (mcp- 4/ccl13)
Structure deposition date
2007-09-14
Thiol separation (Å)
2
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99616
Residue number A
35
Residue number B
74
Peptide name
C-C motif chemokine 13
Ligandability
Cysteine 35 of C-C motif chemokine 13
Cysteine 74 of C-C motif chemokine 13
2ra4 B 12 B 35
A redox-regulated disulphide may form within C-C motif chemokine 13 between cysteines 35 and 58 (12 and 35 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
56
PDB code
2ra4
Structure name
crystal structure of human monocyte chemoattractant protein 4 (mcp- 4/ccl13)
Structure deposition date
2007-09-14
Thiol separation (Å)
7
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99616
Residue number A
35
Residue number B
58
Peptide name
C-C motif chemokine 13
Ligandability
Cysteine 35 of C-C motif chemokine 13
Cysteine 58 of C-C motif chemokine 13
2ra4 B 11 B 12
A redox-regulated disulphide may form within C-C motif chemokine 13 between cysteines 34 and 35 (11 and 12 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
2ra4
Structure name
crystal structure of human monocyte chemoattractant protein 4 (mcp- 4/ccl13)
Structure deposition date
2007-09-14
Thiol separation (Å)
8
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99616
Residue number A
34
Residue number B
35
Peptide name
C-C motif chemokine 13
Ligandability
Cysteine 34 of C-C motif chemokine 13
Cysteine 35 of C-C motif chemokine 13
2ra4 B 35 B 51
A redox-regulated disulphide may form within C-C motif chemokine 13 between cysteines 58 and 74 (35 and 51 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
2ra4
Structure name
crystal structure of human monocyte chemoattractant protein 4 (mcp- 4/ccl13)
Structure deposition date
2007-09-14
Thiol separation (Å)
9
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99616
Residue number A
58
Residue number B
74
Peptide name
C-C motif chemokine 13
Ligandability
Cysteine 58 of C-C motif chemokine 13
Cysteine 74 of C-C motif chemokine 13
2ra4 A 11 A 51
A redox-regulated disulphide may form within C-C motif chemokine 13 between cysteines 34 and 74 (11 and 51 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
2ra4
Structure name
crystal structure of human monocyte chemoattractant protein 4 (mcp- 4/ccl13)
Structure deposition date
2007-09-14
Thiol separation (Å)
9
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99616
Residue number A
34
Residue number B
74
Peptide name
C-C motif chemokine 13
Ligandability
Cysteine 34 of C-C motif chemokine 13
Cysteine 74 of C-C motif chemokine 13
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