ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Neuronal PAS domain-containing protein 1

Intramolecular
Cysteine 319 and cysteine 339
A redox-regulated disulphide may form within Neuronal PAS domain-containing protein 1 between cysteines 319 and 339. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
37
PDB code
5sy5
Structure name
crystal structure of the heterodimeric npas1-arnt complex
Structure deposition date
2016-08-10
Thiol separation (Å)
10
Half-sphere exposure sum ?
65
Minimum pKa ?
12
% buried
79
Peptide accession
P97459
Residue number A
319
Residue number B
339
Peptide name
Neuronal PAS domain-containing protein 1

Ligandability

Cysteine 319 of Neuronal PAS domain-containing protein 1

Cysteine 339 of Neuronal PAS domain-containing protein 1

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