Neurturin
Intermolecular
Cysteine 164 and cysteine 164
Intramolecular
Cysteine 103 and cysteine 165
Cysteine 130 and cysteine 194
Cysteine 134 and cysteine 196
Cysteine 103 and cysteine 134
Cysteine 103 and cysteine 196
Cysteine 103 and cysteine 194
Cysteine 165 and cysteine 196
Cysteine 134 and cysteine 165
Cysteine 165 and cysteine 194
More...Cysteine 130 and cysteine 165
Cysteine 103 and cysteine 130
Cysteine 134 and cysteine 164
Cysteine 194 and cysteine 196
Cysteine 134 and cysteine 194
Cysteine 164 and cysteine 196
Cysteine 164 and cysteine 165
Cysteine 130 and cysteine 196
Cysteine 103 and cysteine 164
Cysteine 130 and cysteine 134
Cysteine 130 and cysteine 164
5mr9 A 164 B 164
A redox-regulated disulphide may form between two units of Neurturin at cysteines 164 and 164.
Details
Redox score ?
78
PDB code
5mr9
Structure name
ligand-receptor complex
Structure deposition date
2016-12-21
Thiol separation (Å)
3
Half-sphere exposure sum ?
72
Minimum pKa ?
7
% buried
64
Peptide A name
Neurturin
Peptide B name
Neurturin
Peptide A accession
Q99748
Peptide B accession
Q99748
Peptide A residue number
164
Peptide B residue number
164
Ligandability
5mr9 B 103 B 165
A redox-regulated disulphide may form within Neurturin between cysteines 103 and 165.
Details
Redox score ?
86
PDB code
5mr9
Structure name
ligand-receptor complex
Structure deposition date
2016-12-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99748
Residue number A
103
Residue number B
165
Peptide name
Neurturin
Ligandability
Cysteine 103 of Neurturin
Cysteine 165 of Neurturin
5mr9 B 130 B 194
A redox-regulated disulphide may form within Neurturin between cysteines 130 and 194.
Details
Redox score ?
84
PDB code
5mr9
Structure name
ligand-receptor complex
Structure deposition date
2016-12-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99748
Residue number A
130
Residue number B
194
Peptide name
Neurturin
Ligandability
Cysteine 130 of Neurturin
Cysteine 194 of Neurturin
5mr9 A 134 A 196
A redox-regulated disulphide may form within Neurturin between cysteines 134 and 196.
Details
Redox score ?
79
PDB code
5mr9
Structure name
ligand-receptor complex
Structure deposition date
2016-12-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
56
Minimum pKa ?
9
% buried
31
Peptide accession
Q99748
Residue number A
134
Residue number B
196
Peptide name
Neurturin
Ligandability
Cysteine 134 of Neurturin
Cysteine 196 of Neurturin
5nmz C 103 C 134
A redox-regulated disulphide may form within Neurturin between cysteines 103 and 134.
Details
Redox score ?
74
PDB code
5nmz
Structure name
human neurturin (97-197)
Structure deposition date
2017-04-07
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99748
Residue number A
103
Residue number B
134
Peptide name
Neurturin
Ligandability
Cysteine 103 of Neurturin
Cysteine 134 of Neurturin
5nmz A 103 A 196
A redox-regulated disulphide may form within Neurturin between cysteines 103 and 196.
Details
Redox score ?
72
PDB code
5nmz
Structure name
human neurturin (97-197)
Structure deposition date
2017-04-07
Thiol separation (Å)
4
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99748
Residue number A
103
Residue number B
196
Peptide name
Neurturin
Ligandability
Cysteine 103 of Neurturin
Cysteine 196 of Neurturin
5mr4 A 103 A 194
A redox-regulated disulphide may form within Neurturin between cysteines 103 and 194.
Details
Redox score ?
69
PDB code
5mr4
Structure name
ligand-receptor complex
Structure deposition date
2016-12-21
Thiol separation (Å)
5
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99748
Residue number A
103
Residue number B
194
Peptide name
Neurturin
Ligandability
Cysteine 103 of Neurturin
Cysteine 194 of Neurturin
5mr4 A 165 A 196
A redox-regulated disulphide may form within Neurturin between cysteines 165 and 196.
Details
Redox score ?
68
PDB code
5mr4
Structure name
ligand-receptor complex
Structure deposition date
2016-12-21
Thiol separation (Å)
5
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99748
Residue number A
165
Residue number B
196
Peptide name
Neurturin
Ligandability
Cysteine 165 of Neurturin
Cysteine 196 of Neurturin
5nmz D 134 D 165
A redox-regulated disulphide may form within Neurturin between cysteines 134 and 165.
Details
Redox score ?
67
PDB code
5nmz
Structure name
human neurturin (97-197)
Structure deposition date
2017-04-07
Thiol separation (Å)
5
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99748
Residue number A
134
Residue number B
165
Peptide name
Neurturin
Ligandability
Cysteine 134 of Neurturin
Cysteine 165 of Neurturin
5mr4 A 165 A 194
A redox-regulated disulphide may form within Neurturin between cysteines 165 and 194.
Details
Redox score ?
67
PDB code
5mr4
Structure name
ligand-receptor complex
Structure deposition date
2016-12-21
Thiol separation (Å)
5
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99748
Residue number A
165
Residue number B
194
Peptide name
Neurturin
Ligandability
Cysteine 165 of Neurturin
Cysteine 194 of Neurturin
5mr9 B 130 B 165
A redox-regulated disulphide may form within Neurturin between cysteines 130 and 165.
Details
Redox score ?
64
PDB code
5mr9
Structure name
ligand-receptor complex
Structure deposition date
2016-12-21
Thiol separation (Å)
5
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99748
Residue number A
130
Residue number B
165
Peptide name
Neurturin
Ligandability
Cysteine 130 of Neurturin
Cysteine 165 of Neurturin
5mr4 B 103 B 130
A redox-regulated disulphide may form within Neurturin between cysteines 103 and 130.
Details
Redox score ?
61
PDB code
5mr4
Structure name
ligand-receptor complex
Structure deposition date
2016-12-21
Thiol separation (Å)
6
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99748
Residue number A
103
Residue number B
130
Peptide name
Neurturin
Ligandability
Cysteine 103 of Neurturin
Cysteine 130 of Neurturin
5mr4 A 134 A 164
A redox-regulated disulphide may form within Neurturin between cysteines 134 and 164. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
5mr4
Structure name
ligand-receptor complex
Structure deposition date
2016-12-21
Thiol separation (Å)
7
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99748
Residue number A
134
Residue number B
164
Peptide name
Neurturin
Ligandability
Cysteine 134 of Neurturin
Cysteine 164 of Neurturin
5mr4 B 194 B 196
A redox-regulated disulphide may form within Neurturin between cysteines 194 and 196. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
5mr4
Structure name
ligand-receptor complex
Structure deposition date
2016-12-21
Thiol separation (Å)
9
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99748
Residue number A
194
Residue number B
196
Peptide name
Neurturin
Ligandability
Cysteine 194 of Neurturin
Cysteine 196 of Neurturin
5mr4 A 134 A 194
A redox-regulated disulphide may form within Neurturin between cysteines 134 and 194. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
5mr4
Structure name
ligand-receptor complex
Structure deposition date
2016-12-21
Thiol separation (Å)
10
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99748
Residue number A
134
Residue number B
194
Peptide name
Neurturin
Ligandability
Cysteine 134 of Neurturin
Cysteine 194 of Neurturin
5mr5 B 164 B 196
A redox-regulated disulphide may form within Neurturin between cysteines 164 and 196. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
5mr5
Structure name
ligand-receptor complex
Structure deposition date
2016-12-21
Thiol separation (Å)
9
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99748
Residue number A
164
Residue number B
196
Peptide name
Neurturin
Ligandability
Cysteine 164 of Neurturin
Cysteine 196 of Neurturin
5mr5 B 164 B 165
A redox-regulated disulphide may form within Neurturin between cysteines 164 and 165. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
5mr5
Structure name
ligand-receptor complex
Structure deposition date
2016-12-21
Thiol separation (Å)
9
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99748
Residue number A
164
Residue number B
165
Peptide name
Neurturin
Ligandability
Cysteine 164 of Neurturin
Cysteine 165 of Neurturin
5mr4 A 130 A 196
A redox-regulated disulphide may form within Neurturin between cysteines 130 and 196. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
5mr4
Structure name
ligand-receptor complex
Structure deposition date
2016-12-21
Thiol separation (Å)
9
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99748
Residue number A
130
Residue number B
196
Peptide name
Neurturin
Ligandability
Cysteine 130 of Neurturin
Cysteine 196 of Neurturin
5nmz C 103 C 164
A redox-regulated disulphide may form within Neurturin between cysteines 103 and 164. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
5nmz
Structure name
human neurturin (97-197)
Structure deposition date
2017-04-07
Thiol separation (Å)
10
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99748
Residue number A
103
Residue number B
164
Peptide name
Neurturin
Ligandability
Cysteine 103 of Neurturin
Cysteine 164 of Neurturin
5nmz D 130 D 134
A redox-regulated disulphide may form within Neurturin between cysteines 130 and 134. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
5nmz
Structure name
human neurturin (97-197)
Structure deposition date
2017-04-07
Thiol separation (Å)
10
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99748
Residue number A
130
Residue number B
134
Peptide name
Neurturin
Ligandability
Cysteine 130 of Neurturin
Cysteine 134 of Neurturin
6gl7 A 130 A 164
A redox-regulated disulphide may form within Neurturin between cysteines 130 and 164. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
32
PDB code
6gl7
Structure name
neurturin-gfra2-ret extracellular complex
Structure deposition date
2018-05-23
Thiol separation (Å)
10
Half-sphere exposure sum ?
79
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q99748
Residue number A
130
Residue number B
164
Peptide name
Neurturin
Ligandability
Cysteine 130 of Neurturin
Cysteine 164 of Neurturin
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