ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Noelin

Intermolecular
Cysteine 221 and cysteine 221
Intramolecular
Cysteine 227 and cysteine 409
A redox-regulated disulphide may form between two units of Noelin at cysteines 221 and 221.

Details

Redox score ?
82
PDB code
5amo
Structure name
structure of a mouse olfactomedin-1 disulfide-linked dimer of the olfactomedin domain and part of the coiled coil
Structure deposition date
2015-03-11
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide A name
Noelin
Peptide B name
Noelin
Peptide A accession
O88998
Peptide B accession
O88998
Peptide A residue number
221
Peptide B residue number
221

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Noelin between cysteines 227 and 409.

Details

Redox score ?
83
PDB code
5amo
Structure name
structure of a mouse olfactomedin-1 disulfide-linked dimer of the olfactomedin domain and part of the coiled coil
Structure deposition date
2015-03-11
Thiol separation (Å)
2
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
O88998
Residue number A
227
Residue number B
409
Peptide name
Noelin

Ligandability

Cysteine 227 of Noelin

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 409 of Noelin

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: