ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Tumor susceptibility gene 101 protein

Intramolecular
Cysteine 73 and cysteine 87
A redox-regulated disulphide may form within Tumor susceptibility gene 101 protein between cysteines 73 and 87. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
40
PDB code
3obu
Structure name
crystal structure of the tsg101 uev domain in complex with a hiv-1 ptap peptide
Structure deposition date
2010-08-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
65
Minimum pKa ?
10
% buried
82
Peptide accession
Q99816
Residue number A
73
Residue number B
87
Peptide name
Tumor susceptibility gene 101 protein

Ligandability

Cysteine 73 of Tumor susceptibility gene 101 protein

Cysteine 87 of Tumor susceptibility gene 101 protein

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