ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

39S ribosomal protein L45, mitochondrial

Intramolecular
Cysteine 80 and cysteine 168
A redox-regulated disulphide may form within 39S ribosomal protein L45, mitochondrial between cysteines 80 and 168. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
32
PDB code
7qh6
Structure name
cryo-em structure of the human mtlsu assembly intermediate upon mrm2 depletion - class 1
Structure deposition date
2021-12-10
Thiol separation (Å)
9
Half-sphere exposure sum ?
70
Minimum pKa ?
12
% buried
97
Peptide accession
Q9BRJ2
Residue number A
80
Residue number B
168
Peptide name
39S ribosomal protein L45, mitochondrial

Ligandability

Cysteine 80 of 39S ribosomal protein L45, mitochondrial

Cysteine 168 of 39S ribosomal protein L45, mitochondrial

If this tool was useful for finding a disulphide, please cite: