ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Uridine diphosphate glucose pyrophosphatase NUDT22

Intramolecular
Cysteine 191 and cysteine 227
A redox-regulated disulphide may form within Uridine diphosphate glucose pyrophosphatase NUDT22 between cysteines 191 and 227. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
43
PDB code
5lor
Structure name
human nudt22
Structure deposition date
2016-08-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
60
Minimum pKa ?
10
% buried
42
Peptide accession
Q9BRQ3
Residue number A
191
Residue number B
227
Peptide name
Uridine diphosphate glucose pyrophosphatase NUDT22

Ligandability

Cysteine 191 of Uridine diphosphate glucose pyrophosphatase NUDT22

Cysteine 227 of Uridine diphosphate glucose pyrophosphatase NUDT22

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