ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Translational activator of cytochrome c oxidase 1

Intramolecular
Cysteine 231 and cysteine 253
A redox-regulated disulphide may form within Translational activator of cytochrome c oxidase 1 between cysteines 231 and 253. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
56
PDB code
5ekz
Structure name
crystal structure of mouse taco1
Structure deposition date
2015-11-04
Thiol separation (Å)
8
Half-sphere exposure sum ?
61
Minimum pKa ?
9
% buried
24
Peptide accession
Q8K0Z7
Residue number A
231
Residue number B
253
Peptide name
Translational activator of cytochrome c oxidase 1

Ligandability

Cysteine 231 of Translational activator of cytochrome c oxidase 1

Cysteine 253 of Translational activator of cytochrome c oxidase 1

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