tRNA-splicing endonuclease subunit Sen34

Intramolecular

A redox-regulated disulphide may form within tRNA-splicing endonuclease subunit Sen34 between cysteines 262 and 291. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

7uxa

Structure name

human trna splicing endonuclease complex bound to pre-trna-arg

Structure deposition date

2022-05-05

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

100

Peptide accession

Q9BSV6

Residue number A

262

Residue number B

291

Peptide name

tRNA-splicing endonuclease subunit Sen34

Ligandability

Cysteine 262 of tRNA-splicing endonuclease subunit Sen34

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.