LIM domain-containing protein 2
Intramolecular
Cysteine 40 and cysteine 43
Cysteine 40 and cysteine 64
Cysteine 67 and cysteine 70
Cysteine 67 and cysteine 88
Cysteine 70 and cysteine 88
Cysteine 43 and cysteine 64
Cysteine 66 and cysteine 67
Cysteine 64 and cysteine 66
Cysteine 40 and cysteine 66
Cysteine 66 and cysteine 70
Cysteine 43 and cysteine 66
2lzu A 43 A 46
A redox-regulated disulphide may form within LIM domain-containing protein 2 between cysteines 40 and 43 (43 and 46 respectively in this structure).
Details
Redox score ?
89
PDB code
2lzu
Structure name
solution structure of limd2
Structure deposition date
2012-10-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
50
Minimum pKa ?
5
% buried
12
Peptide accession
Q9BT23
Residue number A
40
Residue number B
43
Peptide name
LIM domain-containing protein 2
Ligandability
Cysteine 40 of LIM domain-containing protein 2
Cysteine 43 of LIM domain-containing protein 2
2lzu A 43 A 67
A redox-regulated disulphide may form within LIM domain-containing protein 2 between cysteines 40 and 64 (43 and 67 respectively in this structure).
Details
Redox score ?
88
PDB code
2lzu
Structure name
solution structure of limd2
Structure deposition date
2012-10-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
5
% buried
24
Peptide accession
Q9BT23
Residue number A
40
Residue number B
64
Peptide name
LIM domain-containing protein 2
Ligandability
Cysteine 40 of LIM domain-containing protein 2
Cysteine 64 of LIM domain-containing protein 2
2lzu A 70 A 73
A redox-regulated disulphide may form within LIM domain-containing protein 2 between cysteines 67 and 70 (70 and 73 respectively in this structure).
Details
Redox score ?
86
PDB code
2lzu
Structure name
solution structure of limd2
Structure deposition date
2012-10-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
46
Minimum pKa ?
6
% buried
6
Peptide accession
Q9BT23
Residue number A
67
Residue number B
70
Peptide name
LIM domain-containing protein 2
Ligandability
Cysteine 67 of LIM domain-containing protein 2
Cysteine 70 of LIM domain-containing protein 2
2lzu A 70 A 91
A redox-regulated disulphide may form within LIM domain-containing protein 2 between cysteines 67 and 88 (70 and 91 respectively in this structure).
Details
Redox score ?
83
PDB code
2lzu
Structure name
solution structure of limd2
Structure deposition date
2012-10-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
63
Minimum pKa ?
6
% buried
10
Peptide accession
Q9BT23
Residue number A
67
Residue number B
88
Peptide name
LIM domain-containing protein 2
Ligandability
Cysteine 67 of LIM domain-containing protein 2
Cysteine 88 of LIM domain-containing protein 2
2lzu A 73 A 91
A redox-regulated disulphide may form within LIM domain-containing protein 2 between cysteines 70 and 88 (73 and 91 respectively in this structure).
Details
Redox score ?
75
PDB code
2lzu
Structure name
solution structure of limd2
Structure deposition date
2012-10-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
53
Minimum pKa ?
9
% buried
4
Peptide accession
Q9BT23
Residue number A
70
Residue number B
88
Peptide name
LIM domain-containing protein 2
Ligandability
Cysteine 70 of LIM domain-containing protein 2
Cysteine 88 of LIM domain-containing protein 2
2lzu A 46 A 67
A redox-regulated disulphide may form within LIM domain-containing protein 2 between cysteines 43 and 64 (46 and 67 respectively in this structure).
Details
Redox score ?
75
PDB code
2lzu
Structure name
solution structure of limd2
Structure deposition date
2012-10-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
53
Minimum pKa ?
9
% buried
16
Peptide accession
Q9BT23
Residue number A
43
Residue number B
64
Peptide name
LIM domain-containing protein 2
Ligandability
Cysteine 43 of LIM domain-containing protein 2
Cysteine 64 of LIM domain-containing protein 2
2lzu A 69 A 70
A redox-regulated disulphide may form within LIM domain-containing protein 2 between cysteines 66 and 67 (69 and 70 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
2lzu
Structure name
solution structure of limd2
Structure deposition date
2012-10-10
Thiol separation (Å)
9
Half-sphere exposure sum ?
59
Minimum pKa ?
6
% buried
12
Peptide accession
Q9BT23
Residue number A
66
Residue number B
67
Peptide name
LIM domain-containing protein 2
Ligandability
Cysteine 66 of LIM domain-containing protein 2
Cysteine 67 of LIM domain-containing protein 2
2lzu A 67 A 69
A redox-regulated disulphide may form within LIM domain-containing protein 2 between cysteines 64 and 66 (67 and 69 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
2lzu
Structure name
solution structure of limd2
Structure deposition date
2012-10-10
Thiol separation (Å)
7
Half-sphere exposure sum ?
60
Minimum pKa ?
10
% buried
20
Peptide accession
Q9BT23
Residue number A
64
Residue number B
66
Peptide name
LIM domain-containing protein 2
Ligandability
Cysteine 64 of LIM domain-containing protein 2
Cysteine 66 of LIM domain-containing protein 2
2lzu A 43 A 69
A redox-regulated disulphide may form within LIM domain-containing protein 2 between cysteines 40 and 66 (43 and 69 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
2lzu
Structure name
solution structure of limd2
Structure deposition date
2012-10-10
Thiol separation (Å)
10
Half-sphere exposure sum ?
57
Minimum pKa ?
5
% buried
16
Peptide accession
Q9BT23
Residue number A
40
Residue number B
66
Peptide name
LIM domain-containing protein 2
Ligandability
Cysteine 40 of LIM domain-containing protein 2
Cysteine 66 of LIM domain-containing protein 2
2lzu A 69 A 73
A redox-regulated disulphide may form within LIM domain-containing protein 2 between cysteines 66 and 70 (69 and 73 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
2lzu
Structure name
solution structure of limd2
Structure deposition date
2012-10-10
Thiol separation (Å)
9
Half-sphere exposure sum ?
49
Minimum pKa ?
10
% buried
6
Peptide accession
Q9BT23
Residue number A
66
Residue number B
70
Peptide name
LIM domain-containing protein 2
Ligandability
Cysteine 66 of LIM domain-containing protein 2
Cysteine 70 of LIM domain-containing protein 2
2lzu A 46 A 69
A redox-regulated disulphide may form within LIM domain-containing protein 2 between cysteines 43 and 66 (46 and 69 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
2lzu
Structure name
solution structure of limd2
Structure deposition date
2012-10-10
Thiol separation (Å)
9
Half-sphere exposure sum ?
55
Minimum pKa ?
9
% buried
8
Peptide accession
Q9BT23
Residue number A
43
Residue number B
66
Peptide name
LIM domain-containing protein 2
Ligandability
Cysteine 43 of LIM domain-containing protein 2
Cysteine 66 of LIM domain-containing protein 2
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