Mediator of RNA polymerase II transcription subunit 10

Intermolecular

Cysteine 84 and cysteine 115 of Mediator of RNA polymerase II transcription subunit 14

A redox-regulated disulphide may form between cysteine 84 of Mediator of RNA polymerase II transcription subunit 10 and cysteine 115 of Mediator of RNA polymerase II transcription subunit 14.

Details

Redox score ?

PDB code

7emf

Structure name

human mediator (deletion of med1-idr) in a tail-extended conformation

Structure deposition date

2021-04-13

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide A name

Mediator of RNA polymerase II transcription subunit 10

Peptide B name

Mediator of RNA polymerase II transcription subunit 14

Peptide A accession

Q9BTT4

Peptide B accession

O60244

Peptide A residue number

Peptide B residue number

115

Ligandability

Cysteine 84 of Mediator of RNA polymerase II transcription subunit 10

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.