a tool for identifying drug-targetable redox-active disulphides

Ciliogenesis and planar polarity effector 2

Intramolecular

Cysteine 117 and cysteine 132

A redox-regulated disulphide may form within Ciliogenesis and planar polarity effector 2 between cysteines 117 and 132.

Details

Redox score ?

64

PDB code

Structure name

structure of the mouse cplane-rsg1 complex

Structure deposition date

2021-10-27

Thiol separation (Å)

5

Half-sphere exposure sum ?

79

Minimum pK_a ?

9

% buried

92

Peptide accession

Residue number A

117

Residue number B

132

Peptide name

Ciliogenesis and planar polarity effector 2

Ligandability

Cysteine 117 of Ciliogenesis and planar polarity effector 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 132 of Ciliogenesis and planar polarity effector 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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