Centromere protein O
Intramolecular
Cysteine 234 and cysteine 254
Cysteine 123 and cysteine 125
Cysteine 125 and cysteine 181
7pb8 O 234 O 254
A redox-regulated disulphide may form within Centromere protein O between cysteines 234 and 254.
Details
Redox score ?
67
PDB code
7pb8
Structure name
crystal structure of the cenp-opqur complex
Structure deposition date
2021-07-31
Thiol separation (Å)
6
Half-sphere exposure sum ?
59
Minimum pKa ?
9
% buried
17
Peptide accession
Q9BU64
Residue number A
234
Residue number B
254
Peptide name
Centromere protein O
Ligandability
Cysteine 234 of Centromere protein O
Cysteine 254 of Centromere protein O
7pb8 O 123 O 125
A redox-regulated disulphide may form within Centromere protein O between cysteines 123 and 125. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
7pb8
Structure name
crystal structure of the cenp-opqur complex
Structure deposition date
2021-07-31
Thiol separation (Å)
6
Half-sphere exposure sum ?
64
Minimum pKa ?
10
% buried
36
Peptide accession
Q9BU64
Residue number A
123
Residue number B
125
Peptide name
Centromere protein O
Ligandability
Cysteine 123 of Centromere protein O
Cysteine 125 of Centromere protein O
7pkn O 125 O 181
A redox-regulated disulphide may form within Centromere protein O between cysteines 125 and 181. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
31
PDB code
7pkn
Structure name
structure of the human ccan deltact complex
Structure deposition date
2021-08-25
Thiol separation (Å)
10
Half-sphere exposure sum ?
73
Minimum pKa ?
11
% buried
77
Peptide accession
Q9BU64
Residue number A
125
Residue number B
181
Peptide name
Centromere protein O
Ligandability
Cysteine 125 of Centromere protein O
Cysteine 181 of Centromere protein O
If this tool was useful for finding a disulphide, please cite: